Congratulations Heath!

Chromosomal INstability causes chaotic cancer genomes. Making sense of this chaos was hard. Come sit around the fire and listen to our tale of The #17DeadlyCINs a gripping epic of mechanisms of CIN, therapy response prediction and drug target discovery nature.com/articles/s4158… 1/

Simon Young Excited to be at the 2022 IAOO meeting as Simon Young kicks things off by defining the role of genomics in oral cancer management. Curtis Pickering gives a tour de force, highlighting the dominance of tumor suppressor genes and emerging trials testing IAP and HAT inhibitors. #IAOO2022

I’d like to share a thread about a new activity I developed for our incoming graduate students this year. After hearing a lot about the hidden curriculum, I wanted to provide some mechanism to ‘onboard’ our incoming students on topics related to success in graduate school.

I’m hiring postdoc and scientists for my new lab Yale School of Medicine and Yale ENT. We study the translational genomics of head and neck cancer and need bench and computational scientists for our team. If you are interested please DM or email me.

My lab is hiring postdocs and scientists to study the translational genomics of head and neck cancer. We are looking for wet lab, computational, and combination skillsets. postdocs.yale.edu/postdoctoral-p… Come join us Yale University Yale School of Medicine. #hiring #postdoc #postdocposition #postdocjobs

What genomic alterations are associated with treatment response or outcome in HNSCC? I would like to put together a list. Please share your favorites with a PMID. 3 from my lab are: TP53 and chemoXRT: PMID35443062 CASP8 and XRT: PMID33108350 CREBBP/EP300 and XRT: PMID34732714

I voted! So should you.

Very interesting Phase I study from Sana Karam, MD, PhD of SBRT + IO. It includes almost everything except mutation data. 😕 Questions: Does TP53 mutation status matter? How do the cells die? Is there a necroptosis component that induces the immune response? Are CASP8 or cIAPs involved?

Join us for the AACR-AHNS Head and Neck Cancer Conference, July 7-8 in Montreal! Abstract submission deadline is April 20. aacr.org/meeting/aacr-a… Sana Karam, MD, PhD Joseph Califano UCSD Cancer AHNS AACR Foundation

Has anyone used a digital business card? Would you recommend it? Which platform is best for academics?

Yale just increased their starting postdoc salaries to $65,000. Come join my lab at Yale! Contact me if you would like to work on translational genomics of head and neck cancer. Cell/molecular biology and/or computation experience desired. postdocs.yale.edu/policies/postd…

Very useful thread. Know your data. The goal of biological data analysis is not just to find something statistically significant, but to find what is biologically meaningful. Truly understanding the data can help you find the important things within it.

1. This summer I've been thinking a lot about "cognitive load" which is term that has multiple definitions but for me means something like "the amount of processing, analysing, thinking, & deciding I can do in a day before my brain stops working" here's a short thread about that

I haven't been posting much on here lately, and now I'm going to be mostly at the Blue place. There still isn't much of a head & neck cancer community over there, but there can be if you join us. I'm going to be posting a HN paper each week at the Blue place.

I'm going to be posting a HN research paper each week at the Blue place. The first one is up now. It's from the Scheff lab at Pitt. Heath Skinner, MD PhD Nicole Scheff bsky.app/profile/cpicke…

I just posted another HNSCC article over in the Blue place. This one is from the Brakenhoff lab.

I posted another HNSCC article in the Blue place. This is the recent phase 1/2 trial from the Johnson lab.