Nice work on transgenerational inheritance of an epiphenotype. So much evidence for this type of phenomenon, people shouldn't be skeptical anymore rdcu.be/cz0Vr

My lab is hiring a research associate to support multiple large-scale single-cell projects in AD and PD. If you know someone interested, please share. New grads looking for more experience prior to applying to MD or PhD are strongly encouraged to apply! gladstone.wd5.myworkdayjobs.com/careers/job/Sa…

awesome! You don't have to pay for 10X kits to make UMAPs anymore🤣

Could #ecDNA be cancer’s Achilles’ heel? Exciting work today in nature from HHMI Investigators Howard Chang , Robert Tjian, HHMI | Janelia Zhe J. Liu & colleagues: go.nature.com/3nOj6LO Here’s how ecDNAs may contribute to #cancer – & spark new ideas for treatment 🧵 (1/10)

Postdoctoral position in my lab to study the role of non-coding variants in causing neurodevelopmental disorders in response to environmental changes

Looking forward to speaking at the 1st Research Symposium of the Clovis Community College organized by the amazing Rosa Alcazar, who is trying to bring genomics education to all cloviscollege.edu/events/researc…

Very interesting paper with huge implications for the epigenetics field Context-dependent transcriptional regulation by Drosophila Polycomb Response Elements biorxiv.org/content/10.110…

Worth reading. What can we do about the current state of gun laws in the US? Boycotting states with lax laws would be a start. No travel, seminars, or conferences in ultra-red states. Don't buy their products. Any other ideas? science.org/doi/epdf/10.11…

She looks just like me

Incredibly naive understanding of how the system works. Universities will not pay for the increases. PIs will have to hire fewer postdocs and/or will move to non UC institutions

Where is the sailboat?

I've been teaching my 3 year-old granddaughter about TADs. She doesn't understand why they are triangles and not squares

Maybe you are not purifying the sperm properly? We don't find any cell free DNA in sperm preps from the cause epididymis and no differences between treating or not with DNase. Also, no difference with ejaculated sperm after gradient purification

On the origin of the integrity of a subset of Topologically Associating Domains upon Cohesin loss in Interphase Chromosomes biorxiv.org/content/10.110… More proof that there are two types of TADs forming by different mechanisms. Using "TAD" to refer to both of them is confusing.

We have an exciting program with amazing speakers and lots of room for talks selected from the abstracts!!!!!

Very important paper. Everyone planning to use Hi-C to compare changes of interactions between two conditions should read this biorxiv.org/content/10.110…

This is a must-read paper for those interested in chromatin 3D organization. Compartments are way smaller than generally thought