Placebo controlled RCT of 1:1 THC:CBD oil in advance stage cancer finds small benefit in pain, worse wellbeing compared to placebo, no overall improvement in symptom burden. Cannabis oil was associated with more unwanted effects and more adverse effects. pmc.ncbi.nlm.nih.gov/articles/PMC12…

Can psychedelics benefit mental health without the trip? Boris D Heifets is testing ketamine under anesthesia—and challenging assumptions about how these therapies work. Listen now on Up First from NPR: n.pr/4ogOorT

Viewpoint: Ketamine's antidepressant potential is hindered by commercial barriers, highlighting the need for a federal program to prioritize drug repurposing based on patient needs. ja.ma/4eweJ0B

Did you see this recent paper... ⬆️ AEA & ⬇️ 2-AG levels are linked to ⬆️ anxiety in youth SSRI response in teens with GAD was tied to⬆️ 2-AG Could endocannabinoids be biomarkers for anxiety & treatment response? nature.com/articles/s4138…

#ThisWeekInNPP This study explored how prenatal & postnatal THC exposure affects🧠 development & social behavior in 🐭, highlighting an impact on microglial phagocytosis in the developing amygdala in a sex-specific & timing-dependent manner ⏲️ nature.com/articles/s4138…

Behavioral Neuroscience: The consequences of stress on the brain and fear elifesciences.org/articles/108480

Congratulations to this year's cohort of travel awardees. The committee had an incredibly hard job with over 100 applications! We look forward to seeing you all in Spain next month. Attendees, the data blitz highlighting the awardee's work is on Day 1 at 15:10. #EBPS2025

Most viewed this week from JAMA Psychiatry: Low-dose #semaglutide reduced alcohol craving and consumption in adults with alcohol use disorder. ja.ma/4fxVWT4

🚨Update for PIs planning NIH app submissions for Oct/Nov deadlines: Many NIMH NOSIs I'm engaged with are expiring on Sept 8th so plan accordingly! This includes: 1. grants.nih.gov/grants/guide/n… 2. grants.nih.gov/grants/guide/n… 3. grants.nih.gov/grants/guide/n…

An amygdala-cortical circuit for encoding generalized fear memories nature.com/articles/s4138…

Fun collaboration with Margaret Haney is moving to bluesky @MegHaney Cassie Moore Elise Weerts Caroline Arout & Hannah Harris! We evaluated the translational pipeline, from preclinical & human lab models to RCTs for CUD, reviewing medication effects & discussing challenges in translating findings.

Most viewed this week from JAMA Psychiatry: Low-dose #semaglutide reduced alcohol craving and consumption in adults with alcohol use disorder. ja.ma/4lpShbb

Opening keynote of the 2025 Gordon Research Conference on Cannabinoids in the CNS about to kick off with Sheena Josselyn, Harriet De Wit and Matt Hill #CannabinoidGRC2025!

Cannabinoid GRC clinical researchers debating methodology 😬😬😬 THC Vs. Whole plant

Wonderful session on Cannabis, Trauma and Society with AZA Allsop, MD, PhD, Anahita Bassir Nia, Edward Chesney, Gavin Petrie and Nate Harnett with discussant extraordinaire Debra Karhson! #CannabinoidGRC2025

Are hallucinogenic effects critical to the therapeutic benefits of psychedelics? 🆕 Primer by Dr. Albert Garcia-Romeu Johns Hopkins Psychedelic Research Center breaks down what's known about the role of therapy & subjective effects in driving psychedelics' putative efficacy nature.com/articles/s4427…

Here I can take up the whole of the sky, Unfurling becoming my full size Look at me burst through the ceiling Aren’t you so glad you came Breathless and begging And screaming my name florence.lnk.to/everybodyscrea… Everybody Scream Title Track 🪾 Written by Florence Welch, Mark Bowen

And just like that #CannabinoidGRC2025 comes to an end! Big thank you to my co-chair Cecilia Hillard and all the attendees and speakers! Congrats to @mayoonthebrain and @ryanmcpickle on their selection as chairs for the 2029 meeting!