Check out our latest review on late-stage difluoromethylation, out in Chem Soc Rev! A great collaboration with Pfizer Inc. and JNJInnovative Medicine ! Oxford Chemistry SBM CDT. I had a great time working on this together with Claudio Meyer! pubs.rsc.org/en/content/art…

Hydrofluoromethylation of Alkenes and much more out now in Chemical Science! Many congratulations to Sandrine (now Knowles group, Princeton), Claudio (now MacMillan Group), Sebastiano and Jeroen (off soon to Genentech San Francisco) and Xuanxiao pubs.rsc.org/en/content/art…

We are happy to share our newest publication in nature on the 18F-labelling of difluorocarbene and its applications. Congratulations to all involved! Cardiff University School of Chemistry Robert Paton Pfizer Inc. @JanssenEMEA FLUDD Oxford Chemistry UCB News nature.com/articles/s4158…

Nature research paper: [18F]Difluorocarbene for Positron Emission Tomography go.nature.com/3qJ3sCf

Photoproximity Labeling of Sialylated Glycoproteins Reveals Sialylation-Dependent Regulation of Ion Transport David MacMillan MacMillan Group Princeton Chemistry Princeton University #Photoproximity #Sialylated #Glycoproteins #Glycomap #Sialylation #Regulation #IonTransport pubs.acs.org/doi/10.1021/ja…

Check out this preprint on cubanes. Using a convenient approach to cyclobutadiene and copper photoredox catalysis, we are able to access bioisosteres of ortho-, meta-, and para-substituted benzenes for Med. Chem.   chemrxiv.org/engage/chemrxi…

#PrincetonU chemists from the MacMillan Group and the The Muir Lab used two marquee technologies to shine a light on the interactions between biomolecules. bit.ly/40IeuYu

TransitID is out today in Cell! This is a proximity labeling method for unbiased discovery of endogenous proteins that traffick from a defined “source” location to a defined “destination” location. TransitID uses sequential labeling by TurboID in the source, followed by a chase