Enhanced Recognition of a Herbal Compound Epiberberine by a DNA Quadruplex-Duplex Structure biorxiv.org/cgi/content/sh… #biorxiv_biochem

[Preprint at BioRxiv] Recognition of RNA secondary structures with a programmable peptide nucleic acid-based platform biorxiv.org/cgi/content/sh…

biorxiv_biochem Published in the journal Anal Chem: pubs.acs.org/doi/10.1021/ac…

Online now: Recognition of RNA secondary structures with a programmable peptide nucleic acid-based platform dlvr.it/TBqCv7

Mechanistic insights into ASO-RNA complexation: Advancing antisense oligonucleotide design strategies: Molecular Therapy Nucleic Acids cell.com/molecular-ther… --The theoretical work is consistent with our idea of targeting RNA structures with dsRNA-ssRNA junction-specific PNAs.

New RNA Tool Could Offer Opportunities on How We Tackle Deadly Illnesses sciencefeatured.com/2024/12/27/new… Science Featured

Glance a Week 🔬 A New RNA tool may transform how we fight deadly diseases! Researchers have designed dual-affinity peptide nucleic acids capable of targeting complex RNA structures. This breakthrough paves the way for innovative therapies to treat challenging illnesses and

[New Paper] In collaboration with Prof. Ben Zhong Tang et al., Neuronal Tracing and Visualization of Nerve Injury by a Membrane-Anchoring Aggregation-Induced Emission Probe | ACS Nano pubs.acs.org/doi/abs/10.102…

Please RETWEET! 2 postdocs (one chemical biologist, one RNA biologist) and multiple PhD positions are available at #KwokLab, City University of Hong Kong. We work on #RNA, #Gquadruplex, #aptamer , #peptide, #Biosensor and more! See kitkwok.com . PM if interested.

Postgraduate programs, School of Medicine at CUHK-Shenzhen. MPhil-PhD in Biomedical Engineering MPhil-PhD in Biological Sciences Master of Science in Bioinformatics Deadline: May 20, 2025. medpg.cuhk.edu.cn/en/node/25

Happy to interact with peers and students at the CSHA conference. A lot needs to be done on further developing dual-affinity peptide nucleic acids (daPNAs) targeting RNA structures. cell.com/cell-reports-p…

Towards the Development of Isoenergetic Peptide Nucleic Acid Based Probes Targeting Double-Stranded RNAs Through Enhancing ... biorxiv.org/content/10.110… #biorxiv_biochem

A new dual-affinity peptide nucleic acid for targeting miRNA-21 precursor rescues tumor repressor PTEN expression biorxiv.org/content/10.110… #biorxiv_molbio