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Peker, Riemer et al. Universität zu Köln identify a two-step mitochondrial import pathway allowing for dual protein localization to matrix and IMS. Weak targeting signals allow proteins to acquire stabilizing disulfide bonds in the IMS en route to the matrix. bit.ly/3MaULMg

In Science, researchers present MIDAS, a powerful new tool to help improve the discovery and characterization of elusive interactions between proteins and metabolites. scim.ag/2C4

This episode made me think outside the box. What a great way to express your creative side! #AcademicTwitter #Academicchatter

Our work influences us and opens new perspectives on the world around - a beautiful message from JacksonLab. Have you had similar experiences with your work? We’d love to hear! #AcademicChatter #AcademicTwitter #science #podcast

We love what this image Euromit 2023 represents. Knowledge, passion, strength, community & commitment to #mitochondrialdisease patients across the globe. 821 professionals from 38 countries attended the conference. Together we are strong & together we are making a difference.

Interested in a postdoctoral project encompassing genome-wide CRISPR/Cas9 screening and mitochondrial metabolism? Let’s apply for a Marie Sklodowska-Curie Postdoctoral Fellowship. Deadline: 13.09.2023 #msca #postdoc #fellowship #funding

TransitID is out today in Cell! This is a proximity labeling method for unbiased discovery of endogenous proteins that traffick from a defined “source” location to a defined “destination” location. TransitID uses sequential labeling by TurboID in the source, followed by a chase

Our preprint show that knock-in mice with drastically reduced levels respirasomes have normal OXPHOS function and no obvious phenotypes! Very unexpected results indeed! Presented the story at EuroMit. Thanks all coauthors for a very nice collaboration! biorxiv.org/content/10.110…

World Mitochondrial Disease Week mitochondrialdiseaseweek.org

Welcome to the Metabolism seminar on Friday, Oct 13th at 9-11 am, Haartman Institute Lecture Hall 2. Talks on nutrient transporters in cancer and mitochondrial quality control by Arafath (Rafa) Najumudeen and JacksonLab ☕️🍪at 8:30. Spread the word STEMM Research Program Medicine and Health, University of Helsinki Institute of Biotechnology (BI)

Our mapping of the cellular protein #interactome with unprecedented depth is now published nature. Leaps in robust #proteomics and analytic workflows enabled us to perform over 4.000 pull-downs in yeast unraveling the social and structural aspects leveraging #alphafold multimer.

In the latest issue! Problem choice and decision trees in science and engineering dlvr.it/T5V7S5

Please check out out our paper with JacksonLab and Brendan Battersby👇 Supernumerary proteins of the human mitochondrial ribosomal small subunit are integral for assembly and translation cell.com/iscience/fullt… Geoffray Monteuuis Krysia Broda 🔬 Elizabeth Pyman Diego Balboa 1/7

Unique architectural features of mammalian mitochondrial protein synthesis 30-day free access to our new review at: authors.elsevier.com/a/1jE3u3QxxSux… Thanks to all the authors for their insightful contributions and our editor for their kind invitation and guidance.

✨Excited to share our new paper in Cell Reports! ✨We show how cells rely on self-made serine to protect themselves under mitochondrial stress. Huge thanks to my mentors JacksonLab and Anu Suomalainen Wartiovaara 🙏 cell.com/cell-reports/f…

Local de novo synthesis of serine delays mitochondrial muscle disease progression. Tour de force work of Christopher Jackson and ⁦Anastasiia Marmyleva⁩ Anastasiia Marmyleva. Congrats Anastasiia especially for your first 1st author paper! ⁦Anu Suomalainen-Wartiovaara Lab⁩ cell.com/cell-reports/f…