Study categorisation from Stuart Pocock at #PratoAnaes2022 ➡️ WOW! and PHEW! interpreted the same but very different ➡️ PHEW! and DAMN! interpreted differently but virtually the same We need to get wiser, a p-value is no substitute for brain.

Fernando Zampieri : we should revisit the ICU mantra of stopping all the patients home medications when critically unwell #CCR24

Several people have now raised the questions of the PK/PD properties of SGLT2is in the critically ill. Lots of work to do! #ccr24

Are all ketones bad? Fernando Zampieri highlighting potential positive effects of ketones in patients with heart failure. Remains to be seen if there are other populations where ketones may improve organ function? doi.org/10.1161/CIRCUL… #CCR24

Since Critical Care Reviews and #CCR24 have had a couple of win ratio analyses, here’s a little plug for a video I made with C. Michael Gibson MD a few years back that is meant to be an accessible explainer of how it works. Please excuse my hair. It was a different time.

Where does this leave steroids for CAP? Results of REMAP-CAP at odds with those of CAPE COD. Meta-analysis required. #CCR24

Fantastic question about the ethics of when response adaptive randomisation goes wrong. Suitably robust response. Very clear that the remap-cap authors acutely feel this and have taken great steps to ensure miscoding errors wont occur going forward. #CCR24

I think this has been one of the most robust discussions I’ve heard at any #CCR meetings. Truly awesome. Massive kudos to all Critical Care Reviews for creating this forum. #CCR24

I like how the 'Monday morning test' has become part and parcel of the discussions at #CCR24. Fascinating to hear how leaders in ICU integrate evidence into clinical practice. Critical Care Reviews

Beyond one-size-fits-all in cardiogenic shock: microaxial flow pump, VA #ECMO or tailored use of mechanical circulatory support? 🫀VA ECMO should be reserved for selected patients with AMI & extreme CS 🫀 mAFP first? #Impella appears promising for CS due to STEMI & should be

I don’t think Rob Mac Sweeney gets enough plaudits for Critical Care Reviews - his visionary approach to presenting, discussing, and disseminating new knowledge from critical care trials is ann incredible gift to humankind. Thanks Rob! #ccr24

At #CCR24 last week one method that came up was the #SlidingDichotomy method. But what is it and when might it be useful? 1/9 #MethodologyMonday #92

jobs.nhs.uk/candidate/joba… we are recruiting our next SCF NCCU Cambridge UK. Fantastic opportunity to join our team & develop neurosciences and trauma icm expertise Virginia Newcombe David Menon AriErcole Pierce Geoghegan

1/ The #Mater Misericordiae University Hospital is currently experiencing a systems problem which means that it cannot access patients’ Electronic Health Records.

The mass #MEDTwitter exodus to #medsky well and truly underway!

For any budding ICU Researchers out there - come work with us! Critical Care Medicine Academic/Clinical Fellowship - (commencing July 2025). See mater.ie/healthcare-pro… Contact [email protected] for further information.

I reckon one of the best questions about #NOTACS was the about the CO2 footprint. It is highly plausible that HFNP was much worse for the environment. HFNP uses a lot of O2 and producing O2 results in a lot of CO2 emissions #CCR25