 
                                Brumbaugh Lab
@brumbaugh_jb
Assistant Professor @CUBoulderMCDB
ID: 1006724267763994625
13-06-2018 02:25:44
308 Tweet
247 Followers
180 Following
 
        Our work is out today Nature Cell Biology! We show that H3K36 methylation is a critical regulator of cell identity and that its depletion profoundly alters cell fate in diverse contexts. (1/4) nature.com/articles/s4155…
 
         
        Our new review on histone H3 K-to-M mutants is now available online at Development. Thanks to our team at CU, the Development editors, and the reviewers for helping us improve this manuscript and bring it to publication! journals.biologists.com/dev/article-ab…
 
         
        Leveraging dominant-negative histone H3 K-to-M mutations to study chromatin during differentiation and development In this Review, Brumbaugh Lab and colleagues discuss using dominant-negative histone mutations to study histone methylation in development: journals.biologists.com/dev/article/15…
 
                        
                    
                    
                    
                 
        Join our #chromatin #epigenetics #immunology #stemcells research group at Josep Carreras Leukaemia Research Institute (IJC) in Barcelona. Perform your Ph.D. with us through the outstanding conditions provided by the IMMERGE project 👇👇 Marie Skłodowska-Curie Actions. FellowshipBard ResearchersJobs
 
         
        This was a fun discussion on a fundamentally important topic. Many thanks to Martin Pera, StemCellReports, and ISSCR for the opportunity.
 
        A dream of our lab has been to image the full central dogma from a single endogenous gene, all live and with single molecule resolution. After many years we are happy to unveil a beautiful cell line that makes it possible. Check out our preprint (biorxiv.org/content/10.110…)! (1/n)
 
        Where it started vs. How it’s going: Primordial Germ Cell Edition clarklabucla #InternationalWomensDay #WomensHistoryMonth2024 #WinRS
 
                        
                    
                    
                    
                 
         
         
         
        How it started vs how its going: endometriosis #WomensHistoryMonth2024 #WinRS #WomeninRepro Caroline Gargett Diana Monsivais PhD
 
                        
                    
                    
                    
                 
        Our new paper defining the role of H3K36 methylation in regulating cell fate and plasticity is available online: rdcu.be/d5AEc Thanks to Alison Pashos, PhD and our entire team for their tireless work and to the editors at Nature Cell Biology for the opportunity!
 
        💫NEW: Brumbaugh Lab, Dempsey & co show that #H3K36 methylation maintains #intestinal epithelial fate commitment, whereas its suppression induces a plastic state and expression of genes involved in #regeneration. 👉🏿rdcu.be/eayN3 nature.com/articles/s4155…
 
        Beautiful work by the Stadtfeld and Thomas Vierbuchen labs on the role of genetic variation on imprinting and dna methylation stability in mouse pluripotent stem cells cell.com/stem-cell-repo…
 
        Thanks to Swarnabh Bhattacharya and Ramesh Shivdasani for the thoughtful discussion of our work. Check it out in Cell Chemical Biology: cell.com/cell-chemical-…
 
         
        Check out our new work with the Bruno Di Stefano lab! The research focuses on RNA sequestration in the context in cell fate, with a deep mechanistic tie to miRNA-based regulation.
 
         
                         
                         
                         
                        