Our new paper (on the cover!) is out today in Science Translational Medicine !! Although I have only been involved in this work for 5 yrs, this has been an exciting study to be part of that shows roles for miR-21/SATB1/S100A9/NFkB in #COPD UTS Uni Newcastle Research science.org/doi/10.1126/sc… a🧵1/n

Proud promotor of Hannelore Van Eeckhoutte who won the EMBO Mol. Medicine award for her poster on the role of RIPK1 in the pathogenesis of #COPD at the fantastic VIB Translational Immunology meeting #TransImmu21 #VIBConf #ResearchUGent.

Very happy to share our paper in Science Translational Medicine on the miR-21/SATB1/S100A9/NFkB axis in #COPD, another fantastic collaboration with Hansbro Research! And our miR-21 ISH has made it to the cover!! Ghent University Research Dr Richard Kim Pieter Mestdagh. Guy Brusselle. science.org/doi/10.1126/sc…

Happy to share our new research paper in AJP-Lung Cellular and Molecular Physiology on the role of miR-223 in #COPD. First author is Mirjam Roffel, a U4 joint PhD student between Ghent and Groningen. UGent Ghent University Research GRIAC_Groningen

New #EditorialFocus by Drs. Joselyn Rojas-Quintero of Brigham and Women's Hospital and Francesca Polverino (pictured) of University of Arizona Health Sciences considers the role of #miRNA in #COPD induced by #cigarette smoke. Read more: ow.ly/7mz850H8l3i #neutrophils #epithelium

Elevated #microRNA 21 underlies #COPD - reducing it reduces symptoms. Image and research by Dr Richard Kim, Krishna P. Sunkara, Ken Bracke & Andrew G. Jarnicki et al Hansbro Research Centenary Institute in Science Translational Medicine. More on bpod.mrc.ac.uk/archive/2022/1… with MRC Laboratory of Medical Sciences (LMS) & Ant Lewis

Review discusses the mechanisms, efficacy, and safety of biologics for severe asthma. nej.md/3nd0Ivi

A great review by Gerard Koppelman GRIAC_Groningen Research UMCG and Guy Brusselle Ghent University Research on biologics in severe asthma in NEJM. ERS American Thoracic Society (ATS) ATS_RCMB University of Groningen

Longarts prof. Guy Brusselle & team lanceren nieuwe leidraad voor de behandeling van patiënten met ernstige astma. ‘We kunnen nu het succes voorspellen van verschillende behandelingen met monoclonale antilichamen.' 👉doelgerichter, efficiënter en goedkoper bit.ly/3uRoodo

Please see 👇 for a #PostDoc position in my team UGent Pharmacy funded by European Research Council (ERC) #ERCCoG grant RESPIRNA, focusing on the development of bio-inspired RNA #nanomedicines for inhalation therapy. 🙏RT! ugent.be/fw/pharmaceuti…

Here is the formal inception of COPD focus group led by Önder Yildirim and Maor Sauler at #ATS2022! Glad to see this effort kick off and hope it leads to fruitful collaborations and exchange of ideas/resources to improve lives of people w/ #COPD!

Adverse roles of mast cell chymase-1 in #COPD. Well done and great working with Gang Liu Hansbro Research Peter Wark Ken Bracke Imperial College London ERS publications ERS Respiratory Translational Research Group Monica (Wenying) Lu Mathew Suji Eapen erj.ersjournals.com/content/early/…

Our paper on RIPK1 kinase-dependent inflammation and cell death in COPD by Hannelore Van Eeckhoutte is out in print in the ERJ! Great collaborative effort with Hansbro Research Önder Yildirim Tom Vanden Berghe Ghent University Research COPD COPD_iNET ERS publications erj.ersjournals.com/content/61/4/2…

Many thanks to Didier Cataldo for the amazing editorial on our paper! COPD Ghent University Research ERS publications erj.ersjournals.com/content/61/4/2…

Amazing PhD defense by Hannelore Van Eeckhoutte, studying the role of regulated cell death in COPD #proudpromotor #COPD Ghent University Research UGent Geneeskunde & Gezondheidswetenschappen

We found more potentially beneficial bacteria in the lungs, and they act in synergy to inhibit pathological inflammation in a 3-D lung cell culture model. Congrats to PhD student Ellen Goeteyn on her first paper and many thanks to our collaborators! frontiersin.org/articles/10.33…

A beautiful editorial to accompany the previous paper by Francesca Polverino et al. bit.ly/3CY7Bbb

Here, we leverage on spatial transcriptomics + proteomics + lung imaging integration to dissect the nature of the adaptive immune compartment in emphysema #COPD atsjournals.org/doi/abs/10.116…

I am exciting to share our large collaborative paper on TLR7 regulates lung damage in #COPD via mast cell tryptase has published in Nature Communications nature.com/articles/s4146… Thank you very much to all authors for their contributions Tatt Jhong Haw Malcolm Starkey 🏴󠁧󠁢󠁷󠁬󠁳󠁿🇦🇺🥋🥼 Hansbro Research

Animal research at #UGent: behind-the-scenes look at the animalarium. Top research and care for animal welfare go hand in hand in the animalarium, the state-of-the art laboratory animal facility on the UZ Gent UGent Geneeskunde & Gezondheidswetenschappen campus. youtube.com/watch?v=i3UvSv…