Metformin for MPN: teaching an old drug new tricks ow.ly/Tq1550T7Mfr #healthservicesandoutcomes #myeloidneoplasia

The preceding profiles of acute GVHD have the potential to help in predicting the future occurrence of chronic GVHD and its severity. ow.ly/l2NQ50T7MlE #transplantation #immunobiologyandimmunotherapy

Strategies to prevent graft failure in haploidentical HCT need to be investigated. ow.ly/Psfy50T7MsB #transplantation #myeloidneoplasia

These data provide a strong rationale for the development of consolidation protocols aimed at enhancing Vγ9Vδ2 T-cell responses. ow.ly/4jre50T7ME3 #immunobiologyandimmunotherapy #myeloidneoplasia

CAR T-cell toxicities: from bedside to bench, how novel toxicities inform laboratory investigations ow.ly/ZAIq50T7MNS #clinicaltrialsandobservations #transplantation

Beyond BCMA: newer immune targets in myeloma ow.ly/HMvC50T7MWr #immunobiologyandimmunotherapy #lymphoidneoplasia

Hypogammaglobulinemia, infections/severe infections, and antimicrobial use were decreased in patients with CLL or NHL treated with IgRT. ow.ly/tCYK50T7N6E #lymphoidneoplasia #healthservicesandoutcomes

Tumor-associated macrophages repolarization and epigenetic regulators may open new therapeutic options for the fight against BL lymphoma. ow.ly/MYyM50T7NbP #lymphoidneoplasia #immunobiologyandimmunotherapy

MCL and infiltrating T cells show enhanced MAPK in the presence of CD163+ macrophages. ow.ly/zOyW50T7Nja #lymphoidneoplasia

The 10-year HGT cumulative incidence rate was 4.87% in FL and 2.95% in MZL. ow.ly/SK4E50T7Nna #lymphoidneoplasia #clinicaltrialsandobservations

Lymphodepletion delays naive T cell (Tn) recovery resulting in lower T-cell receptor repertoire and higher Treg:Tn ratio. ow.ly/wyP250T8FNr #clinicaltrialsandobservations #transplantation

Exchange transfusion is used for SCD complications, but there is inadequate evidence of its safety and benefit in pregnancy. ow.ly/EhhB50T8G1N #clinicaltrialsandobservations #redcellsironanderythropoiesis #transfusionmedicine

Survival was similar and time to infection was longer in patients ending sFU compared with those who continued. ow.ly/YEyV50T8Gib #clinicaltrialsandobservations #healthservicesandoutcomes #lymphoidneoplasia

Consistent with erythrocyte pyruvate kinase activation, adenosine triphosphate increased, and 2,3-DPG decreased with etavopivat treatment. ow.ly/TaMW50T8GPu #clinicaltrialsandobservations #redcellsironanderythropoiesis

Metformin use was associated with a significant decrease in risk of MPN, with the largest effect observed for the ET and PV subtypes. ow.ly/JE6X50T8H4e #clinicaltrialsandobservations #myeloidneoplasia

Commercial CAR T-cell therapies including CARs with CD28 domain may be given safely as outpatient without intense home monitoring. ow.ly/Jlrr50T8Hcc #healthservicesandoutcomes #lymphoidneoplasia

Patients excluded from clinical trials of DLBCL are at a higher risk of dying from lymphoma when treated with standard-of-care therapy. ow.ly/Ihbt50T8HsO #healthservicesandoutcomes #lymphoidneoplasia

The antibody traps a semi-extended conformation of αIIbβ3 and inhibits fibrinogen binding via an allosteric mechanism. ow.ly/yWqn50T8HTV #plateletsandthrombopoiesis #thrombosisandhemostasis

ADAMTS13 exome/genome data from 807 162 gnomAD population was analyzed to establish worldwide/within-population prevalence of hereditary TTP. ow.ly/oY1S50T8Iff #thrombosisandhemostasis #plateletsandthrombopoiesis

The prevalence of RBC abs increased from 2010 to 2021; RBC abs high risk for HDFN were identified in 74.3% of pregnancies. ow.ly/XZY550T8ME0 #transfusionmedicine #immunobiologyandimmunotherapy