Very excited to be at the Biophysical Society 2024 meeting and an honour to be chair elect for the BPS IDP Subgroup subgroup for the 2025/2026 period. Looking forward to contribute to the society for the upcoming years!

Further evidence of high-resolution capabilities at 100 keV with a side-entry cryo holder using the Gatan Microscopy Alpine detector. It even performed better than the K3 on a small sample - Great collab with colleagues in Verba lab UC San Francisco biorxiv.org/cgi/content/sh…

Making a commitment here that I’ll talk about symmetric protein design from a perspective you couldn’t have read about somewhere 😉

Important update! Rosetta Commons has transitioned to a new #PublicRepository, expanding access & #collaboration in #ScientificResearch. Moving the repository brings the exciting possibility for contributions. The new repository is accessible at github.com/RosettaCommons…

Kicking off the 2024 Cold Spring Harbor CryoEM course CSHL Courses! It’s going to be a grueling but amazing 2 weeks!

for the folks who missed Erin Yang give a truly stellar seminar last week, you can how check out the recording 👇 youtu.be/FX7yBJKQuPg

Hey Motorola Support how can I get a replacement for my modem that is still in warranty? The app doesn't work, both of your phone lines are constantly busy, I can't even dm you. Posting at support is all I can do. Seriously?

Our first foray into the fascinating field of DNA repair! Congrats to postdoc Chris Zerio Chris Zerio, who tested hundreds of oligos to identify one that trapped the helicase of human Polymerase θ in the process of annealing two strands of DNA. tinyurl.com/jaddar9u

Thrilled to share my postdoctoral work in @Landerlab! The human Polymerase θ helicase undergoes conformational rearrangements to facilitate DNA microhomology annealing. These insights enable rational design of novel BRCA-deficient cancer therapeutics! tinyurl.com/jaddar9u

Thrilled to share that I will be joining the Faculty of UVA this August. We’re seeking enthusiastic candidates at all levels to join our team. If you’re interested, please reach out.

Finally our work on designing pH responsive antibody nanoparticles capable of disassembling at ~tunable~ pH, packaging and releasing cargo, and targeting specific cell surface receptors is out in NatureStructMolBiol! nature.com/articles/s4159…

New paper published in formal journal ! With Nacho Sánchez and @eagalpern we explore the possibility of existence of extraterrestrial proteins. In sum: likelly! pnas.org/doi/10.1073/pn…

Excited to share that I am starting a lab focused on deep learning-based protein design, biophysics and fundamental biology at Max Planck Institute of Biochemistry (MPIB) and Gene Center Munich in Munich with the Emmy Noether Programme this summer. Join us as a PhD or postdoc. More to follow soon!

Big News! Arzeda has closed a $38M oversubscribed funding round! This investment was led by top investors like Sofinnova Partners, Fall Line Capital, and & W.L. Gore & Associates tinyurl.com/bdemjjeh

Some thoughts on the current state of single particle cryo-EM map/model validation. (TLDR: preferred orientation remains a big problem, ❤️ Q-scores. There's been progress, but there's still more to do. ) authors.elsevier.com/sd/article/S09…

Come be my colleague! UW Tacoma is hiring an Assistant Professor of Biochemistry. We're looking for someone excited about mentoring undergraduates in research, inclusive teaching, and being part of an interdisciplinary community of scholars. apply.interfolio.com/154390

This is a huge validation of the importance of protein design. Arzeda cofounder David Baker is a gratifying choice. This signals the arrival of protein design as a fundamental tool in chemistry. I spent my PhD working on enzyme design.. and look where we are now!

Huge congratulations to David Baker, Arzeda Co-Founder and Scientific Advisor, for being awarded the 2024 Nobel Prize in Chemistry! 🏆 Arzeda is the first protein design company to emerge from David's lab, contributing to breakthroughs in the field. nobelprize.org/prizes/chemist…

The human mitochondrial ClpXP is uniquely assembled and regulated compared to its bacterial counterparts. Congrats to Kelly Chen on her years of hard work on this challenging complex! biorxiv.org/content/10.110…

Delighted to share that our cryo-EM work with Inmunova on engineered immunogens capable of eliciting neutralizing antibodies against hemolytic uremic syndrome is featured on the cover of Protein Science! 🔗 doi.org/10.1002/pro.70…