Our latest paper on prebiotic peptide synthesis in water J. Am. Chem. Soc. pubs.acs.org/doi/10.1021/ja… by Jyoti singh Daniel Whitaker Benji Thoma Saidul Islam @DrCallumFoden Abil Aliev @SheppardTomD UCL Chemistry UCL

Great to be a part of this work ! We dug deeper into thiol-catalysed peptide ligations and amidine hydrolyses , finding a lovely alpha-regioselective lysine ligation 🧪🔎 (sadly no nitrile emoji )

Really cool work Jake Aquilina !! !

Congratulations! Great to see this finally out

netflix should create shared film lists just as spotify blends can do for music playlists. @Netflix please pay me £10 for this idea

Fully funded 4-year PhD available in our Matthew Powner group & with @SheppardTomD UCL Chemistry or please retweet findaphd.com/phds/project/a… ucl.ac.uk/chemistry/stud…

Very happy to see this finally out! Here we interrogate why life codes for some amino acids and not others , through the lens of nonenzymatic peptide synthesis in water 💧 Matthew Powner J. Am. Chem. Soc. pubs.acs.org/doi/10.1021/ja…

Confusing that this would make acetylfetanyl , but then the result name is actually methadone? Also surely you can't reflux Ac2O at 60

PDRA opportunity in our group UCL Chemistry to develop & characterise ribozymes that harness primordial chemistries. 28 months, funded by BBSRC & Royal Society; org chem or mol bio background. Apply by 7th August: tinyurl.com/4bhhf2v2

AT does not look at selection "due to chemical kinetics and catalysis" because it is "chemically agnostic". This is the main problem for me

Awesome work from Jasper, Saidul Islam Jyoti Singh Kreso Bucar Matthew Powner deconvoluting the "weird" structure of pantetheine ! science.org/doi/abs/10.112…

Happy and super excited to share our discovery of a protein fractal! We unravel the surprisingly simple emergence of these marvellous structures and show it might have even been an accident of evolution. Read the full story here nature.com/articles/s4158… Or just stick around 🧵

Excited to share the first paper from my PhD JACS Au. Cysteamine-strecker reaction spontaneously forms peptides in water by highly selective intramolecular thiol catalyst. Thanks to my supervisor Matthew Powner and the lab members. pubs.acs.org/doi/10.1021/ja…

Have you ever been curious about prebiotic chemistry but didn't know where to start? Start here! Today our Resident Lecturer Dr. Benji Thoma joins us to give an Introduction to Prebiotic Chemistry, with a focus on nucleic acid synthesis! youtu.be/Mi6ybPFtt7w

Congratulations to Benji Thoma on winning the RSC Chemical Biology poster prize at the 8th Cambridge Symposium on Nucleic Acids #CamNA24 Benji Thoma RSC Chemical Biology

Out today in nature : nature.com/articles/s4158… One step closer to understanding the origin of protein synthesis !