The final open-access version of our Annual Reviews on the ubiquity of polyploidy and its common rules is now available! So fun to work with colleagues from the plant Soltis Lab @UF and cancer Timour Baslan MorrisLabUNC fields! annualreviews.org/content/journa…

If you like Wallace's tweetorial and are going to ASCB, look out for my talk Tues. Dec 17th on how the microtubule cytoskeleton dictates RNA regionalization in Stentor! #cellbio2024 #stentor #protist #NIHMOSAIC

We exposed yeast to -196 C freeze-thaw (without cryoprotectants) and interesting things happened -- the survival went up from about 1% to close to 80% in just 25 cycles! The preprint is out and feedback is highly welcome -- biorxiv.org/content/10.110…

Very important study & call for higher standards shorturl.at/lUbzF It'ld be good to hear CZI Science and nature say about this, which could be deemed #DataPolution. To think that some people want to use AI on this data to understand the cell! How can we sort this out?

Excited to share this review on chromatin-metabolism crosstalk, lead by our star student Varun Sahu. Here, Varun summarizes the molecular principles governing metabolite-chromatin interaction & highlights emerging technologies that could advance the field. There’re lots to learn!

Hello everyone! I am helping to organize a one-day symposium on fluorescent metabolite biosensors and their use in metabolism research. It will be May 12-13 and associated with the Cold Spring Harbor Laboratory “Mechanisms of Metabolic Signaling” Symposium. Our field needs to be

Our review on genetically encoded CDK biosensors is finally out in CSF! Take a look! jstage.jst.go.jp/article/csf/ad…

This is the most important paper in the circadian field in over a decade. A completely new clock component that is evolutionarily conserved. Erquan Zhang Susan Golden @ Society for Research on Biological Rhythms rdcu.be/efxV8

🚨New paper alert!🚨 Our latest work uncovers how cells detect and destroy defective ribosomes before they cause harm. A key quality control pathway with implications for development and disease. #ribosome #qualitycontrol Check it out in Molecular Cell: authors.elsevier.com/a/1l2MA3vVUPVa…

I’m happy to share that my latest PhD work is published in The EMBO Journal! We demonstrate a fundamental role for Annexin A5 in regulating mitochondrial calcium signaling and apoptosis. embopress.org/doi/full/10.10…

Join the #VosshallLab as a postdoctoral scientist! Fully funded position in New York City Rockefeller University hhmi.wd1.myworkdayjobs.com/en-US/External…

Excited to share our new paper! mtDNA mutations contribute to mitochondrial disease and aging only if they rise in abundance. We show that deleterious mutations reach high abundance by hitchhiking on genomes that have a replicative advantage rdcu.be/eugVO

In case this is not obvious: Expecting to understand and predict human biology based solely on modelling nucleic acids is naive. It’s unrealistic.

I'm pleased to share this work now published in PLOS Biology! Since our preprint, we've uncovered exciting new links connecting CCDC66 to actin, vesicular trafficking, and Wnt signaling, and revealed how these contribute to CCDC66's ciliary functions. See link below!

I think a good rule of thumb is to spend at least as much time thinking about your data as you did obtaining it. It's common for people to spend a lot less time thinking than doing which gives rise to all kinds of problems.

🚨Thrilled to announce I will be presenting our work at the Cold Spring Harbor Genome Engineering: CRISPR Frontiers Meeting (Cold Spring Harbor Laboratory) Aug 12–16! 🧬✨ We're combining cutting-edge in vivo CRISPR strategies with cancer research to uncover how mutant p53 drives metastasis—mutation by

#Postdoc opportunity at Columbia U. in New York! We are interested in candidates from biochemistry backgr. & excited about fractionation, purification and reconstitution to study autonomous clocks in the cell cycle, in colab. w/ Aydin Lab at NYU! hhmi.wd1.myworkdayjobs.com/External/job/C…

If you're finishing PhD soon and thinking of postdocs, see below! Especially if you're keen on combining biochemistry, imaging and cell biology, we are onto some exciting findings on molecules and mechanisms underlying a cytoplasmic division cycle autonomously of CDKs!!

Here’s to all my colleagues rocking bowties! Happy #BowtieDay! Shoutout to Sandra Boynton for the image. #Style #WorkLife

If you’re around in NYC, and studying microtubules or mitosis, this one is not to be missed!