Happy to share my recent publication is highlighted in ChemistryViews! chemistryviews.org/stabilizing-th…

Excited to share our story on cross-beta epitope mimics targeting tau propagation, out now in J. Am. Chem. Soc.. Grateful to all involved on this project, and a special congrats to first author Ben Rajewski!! pubs.acs.org/doi/10.1021/ja…

Had an amazing time at the Purdue University Notre Dame Symposium (PUNDS). There were so many great talks/research being done from each university. With that being said, I am honored to receive the Best Presentation Award for my talk!

Largest pharma companies by market cap: 🇺🇸 Eli Lilly: $581b 🇩🇰 Novo Nordisk: $449b 🇺🇸 J&J: $355b 🇺🇸 Merck: $259b 🇺🇸 AbbVie: $244b 🇨🇭 Roche: $213b 🇬🇧 AstraZeneca: $197b 🇨🇭 Novartis: $193b 🇺🇸 Pfizer: $163b 🇺🇸 Amgen: $142b

This U.S. Antibiotic Awareness Week, CDC is committed to highlighting the need for stewardship activities that improve #antibiotic prescribing practices and incorporate a health equity focus. Learn more: bit.ly/2UBQ3LO #BeAntibioticsAware #USAAW23

I am excited to share that my most recent publication was selected to be the front cover of ChemMedChem!

At last... we're thrilled to send our story on macrocyclic mini-tau seeds out into the world. Organic chem, protein mimicry, cryo-EM, cell function; something for everyone! Congrats to Isaac & Xueyong, and collabs from Purdue and IUSM! chemrxiv.org/engage/chemrxi…

Excited that the story of Merck’s Ph 3 oral PCSK9 inhibitor, told by my friend and colleague David Thaisrivongs at #NOS2023ND, is online ACS Organic Division! The Largest Small Molecule: How Chemistry Enabled the Discovery and Development of PCSK9 Inhibitor MK-0616 organicdivision.org/nos-2023-lectu…

The #MorganLabatND celebrated Johann Roque yesterday! He received the Chemistry-Biochemistry-Biology Interface Training Fellowship!! 🥳🥂 We look forward to seeing what Johann accomplishes over the next year, as he works toward synthesizing selective chemical probes for hnRNP H.

Amazing to see efforts to combat antimicrobial resistance is making a comeback in big pharma. Great job Eli Lilly and Company

Me weighing out DCC

Timely and concerning data from The Lancet. Drug-resistant infections know no borders. Every country is at risk. The response to the #AntimicrobialResistance challenge will only be successful if leaders commit to implementing specific, outcome-oriented actions and targets.

If you like total synthesis and Wordle, check out Synthordle, a retrosynthetic analysis game created by Shenvi Lab associates Kevin Zong (GS 2) and Jonah Luo (HS sophomore!). rshenvi.github.io/synthordle/ Coming to Scripps Research Chemical Synthesis class in Winter ’25.

Congrats to Avraz Anwar, whose total synthesis of marformycins A&D appeared in in J Org Chem/Org Lett! Special thanks to Yassin and collaborators in the Richard H. Ebright lab. doi.org/10.1021/acs.or…

Regardless of whether you think this metric is the best proxy for measuring true science impact, US academics and more importantly policy makers should be getting worried as many other data suggest that this is the first time since WW2 we are taking a back seat in so many fields.

I am so excited to present my data in group meeting tomorrow that I can’t sleep. This data will have such an enormous impact for our lab, relieving a LOT of synthetic burden while also yielding incredibly pure peptides! A very fun process chem side project :)

Now live on ChemRxiv! We've developed a new approach that enables us to synthesize N-amino peptides in a fraction of the time compared to previous methods. By optimizing cleavage conditions, we eliminated many byproducts, resulting in highly pure peptides. chemrxiv.org/engage/chemrxi…

I am grateful to be recognized as a Next Gen Leader in Chemistry by Merck ! I look forward to meeting with the scientists who continue to inspire me by their wonderful research and leadership. A huge thanks goes to Del Valle Lab for outstanding mentorship and support.

My latest publication is now online in J Org Chem/Org Lett ! Since developing this protocol, our lab has significantly reduced organic solvent usage (>20x less EA) saving us thousands of dollars and lots of time. doi.org/10.1021/acs.jo…

Check out this Just Accepted paper from Avraz Anwar describing a streamlined synthesis of N-amino peptides. This general protocol will vastly accelerate studies on amide-to-hydrazide replacement in peptides. Congrats, Avraz! doi.org/10.1021/acs.jo…