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I’ve been wondering why Thorlabs doesn’t have an AI platform where we can chat about our idea of mounting something on the microscope or making some changes to the beam path. Then it could give a list of optomechanics that would work for that purpose.

When you go to the lab after a long holiday!

To look into: a Python alternative to ZEMAX... github.com/HarrisonKramer…

May the 4th be with you!

Does anyone have a CAD design for Olympus IX71 or just the nosepiece?

Welcome to Wolfson's first-ever Giving Day! 🎉 With matched funding available and challenge gifts to unlock, take a look at the link below to find out how you can get involved: givingday.wolfson.cam.ac.uk #WolfsonRingsTrue

SOALSI (Single-Objective Airy Light-Sheet Imaging) pubs.acs.org/doi/full/10.10…

Postdoc position available! This is a 2-year post funded by the Academy of Medical Sciences. You'll be based in the Centre for Bacterial Cell Biology here in Newcastle, using super-resolution microscopy to look at the bacterial cell wall. 🔬🦠 RT 🙏 jobs.ac.uk/job/DMY885/res…

Imaging with different acquisition settings. Denoised, Denoised+, exposure time 3 s, full exposre with illumination+.

They sailed for the Antarctic.

science.org/doi/abs/10.112…

SMLM shows us how close molecules are, but just because two molecules are close doesn’t mean they’re bound. This new probabilistic framework changes that. They can actually quantify interactions at the single-molecule level. Fascinating! pnas.org/doi/full/10.10…

Silicon-assisted interferometric Localization Microscopy (SiLM) Clever chip engineering for interferometric SMLM. It sounds an alternative if you can’t build 4Pi/iPALM. Would love to see some FRC-based resolution comparisons to really benchmark it. biorxiv.org/content/10.110…

That’s a 3D projection of a double-helix PSF in Eurovision.

web.stanford.edu/group/moerner/…

Claim to deliver 10 nm in xy an 25 nm in z loc precision (no FRC provided?). Photon-efficient and 100x faster (!), compared to what? biorxiv.org/content/10.110…

Could we create a platform for tracking analysis that all these new, cool tools could be on? biorxiv.org/content/10.110…

🐦‍⬛

Behavioural FISH: when you get perfect alignment despite mismatched templates