Super excited to share our work on 7SK core RNP structures and conformational switching published Molecular Cell. These cryo-EM structures are the first for 7SK RNP, providing structural and mechanistic insights for 7SK RNP assembly and P-TEFb regulation. authors.elsevier.com/c/1ena73vVUPK7…

Cell transcriptomic atlas of the non-human primate Macaca fascicularis nature.com/articles/s4158…

Hot off the press! Collab with Sizun Jiang and Garry P. Nolan investigating immune suppressive tissue niches in non-human primate SIV. Congrats Sizun! cell.com/immunity/fullt…

For those who thought the whole tRNA-ribosome-translation thing was so unnecessarily convoluted: peptide synthesis directly on non-canonical RNA bases in tRNA and rRNA. nature.com/articles/s4158…

Amazing and inspiring CSHL Retroviruses meeting keynote speech by Carol Carter!! (A distinguished virologist and a Yale alumnus!) Simon Lab (ISMMS) @stuartjdneil #cshlretro news.stonybrook.edu/university/car…

An excellent job opportunity: Our Dept is recruiting an Assistant Professor or Associate Professor of Immunology or Virology Department of Microbiology and Immunology Carver College of Medicine University of Iowa. Thanks for retweeting! Apply for the faculty position: jobs.uiowa.edu/faculty/view/7…. More info is here: medicine.uiowa.edu/microbiology/

Our paper on the prefusion Rabies glycoprotein is now out in Science Advances! Excellent work from a twitterless Heather Callaway et al. shows a promising step forward in designing better vaccines for Rabies. Link: science.org/doi/10.1126/sc…

👀 Sneak a peek at the deepest & sharpest infrared image of the early universe ever taken — all in a day’s work for the Webb telescope. (Literally, capturing it took less than a day!) This is Webb’s first image released as we begin to #UnfoldTheUniverse: nasa.gov/webbfirstimage…

No one entity can #EndAIDS alone. Through close collaboration & partnership, #PEPFAR has made significant progress toward ending #HIV as a public health threat. The last mile is the greatest challenge, & we must work closely & keep focus on our shared #EndAIDS2030 goal. #AIDS2022

New: Viral suppression and HIV-1 drug resistance 1 year after pragmatic transitioning to dolutegravir first-line therapy in Malawi: a prospective cohort study by Birgit Schramm and colleagues Epicentre_MSF thelancet.com/journals/lanhi… #openaccess

A postdoc position is available now via the NIH T32 Immunology Postdoctoral Training Program University of Iowa. Candidates must have a doctoral degree and the US citizenship or permanent residency. Please contact Drs. Noah Butler and Li Wu Department of Microbiology and Immunology for details. medicine.uiowa.edu/microbiology/r…

Delighted this study in Nature Communications is finally out. Lots of amazing authors contributed to this huge body of work showing control of viral induced inflammation by IFITM3 & it’s interactor Nogo-B nature.com/articles/s4146… Ian Humphreys Systems Immunity Research Institute Cardiff University School of Medicine College of BLS 🧵

BREAKING🔔 The 11th paper from G2P-Japan🇯🇵 is out at STAR Protocols STAR Protocols . Here we summarized the protocol to quantify the fusogenicity of SARS-CoV-2 spike protein. This study/paper was led by Dr. Terumasa Ikeda in Kumamoto U. Please RT! sciencedirect.com/science/articl…

Check out our latest work! We structurally characterized germline versions of the VRC01-class bNAb, BG24, bound to #HIV Env using #CryoEM. This work reveals mechanisms of germline binding, informing #vaccine design! Great work by our graduate student, Kim! nature.com/articles/s4146…

💥Our new paper just out Science Magazine! Antiviral activity of a human protein of retroviral origin A study led fearlessly by John Frank We propose that the human genome encodes a deep pool of antiviral proteins derived from retroviruses! science.org/doi/10.1126/sc…

Please join me and @AmitSharmaOSU in Palm Springs for this fun #retrovirus meeting with a fantastic line up of keynote speakers, including Priyamvada Acharya Rahm Gummuluru Yong Xiong Lab !

I am excited to share that I have joined the Department of Population Health and Pathobiology NC State Vet Medicine as an Associate Professor. Our research lab is focused on Animal Models of HIV Infection and Coronavirus Drug Discovery with the goal to improve human and animal health.

Check out special research collection led by Duke Center for HIV Structural Biology affiliated investigators, Maolin Lu, Amit Sharma & Sophie Gobeil frontiersin.org/research-topic… Aligned with Duke Center for HIV Structural Biology objectives the collection invites submissions of Original Research, Reviews & Mini-Reviews

HOW WE'RE FIGHTING VIRUSES. Dr. Amit Sharma's research at #NCStateVetMed dives into viral-host interactions to prevent & treat infections. By understanding how viruses work, his team develops vital antivirals & vaccines for both people and pets. MORE: go.ncsu.edu/rr-may25