PerturbSci-Kinetics for high-throughput functional characterization of RNA dynamic regulators is published today Nature Biotechnology, led by fantastic Zihan Xu from our lab Rockefeller University!

Beautiful work by our collaborator ⁦Hite Lab⁩ determining the structural basis of Flvcr1-mediated transport. Single mutation can uncouple choline and ethanolamine transport. ⁦Rockefeller University⁩ ⁦Memorial Sloan Kettering Cancer Center⁩ biorxiv.org/content/10.110…

How does mitochondria sense and control their glutathione levels? Our new work Science Magazine by a fantastic student Yuyang Liu describing a redox metabolite sensing mechanism for mitochondria. Rockefeller University The Mark Foundation for Cancer Research science.org/doi/10.1126/sc…

(Thrilled to have my first Twitter Thrill) Thrilled to share my first paper published today ⁦Science Magazine⁩. How does a cell monitor metabolic homeostasis across so many subcompartments? We tried to offer a hint by looking at GSH in mitochondria. science.org/doi/10.1126/sc…

Congrats Rebecca Timson for generating a mouse model to study GSH limitation in vivo. Rockefeller University sciencedirect.com/science/articl…

Following up our work describing FLVCR1 as a high affinity choline transporter Kivanc Birsoy Artem Khan, excited to share our recent work in close collaboration with Yeeun Son Hite Lab describing the structure and mechanism of action of FLVCR1! nature.com/articles/s4158…

New work from our lab’s genomics guru Artem Khan with Eric R. Gamazon. Artem generated a new platform for metabolic gene discovery and identified the mitochondrial choline transporter. Rockefeller University Nature Genetics nature.com/articles/s4158…

A novel platform for identifying metabolic gene functions from Kivanc Birsoy has already revealed interactions between proteins and metabolites that are fundamental to cell metabolism. Nature Genetics #RockefellerScience rockefeller.edu/news/36160-new…

Thrilled to finally share an amazing discovery made during my PhD Kivanc Birsoy's lab. We found that glycosphingolipids in the plasma membrane of cancer cells impact how sensitive they are to immune cells. nature.com/articles/s4158…

Excited to share my first work in Junyue lab describing next generation, imaging free spatial transcriptomics-“IRISeq”. With IRISeq, we are able to perform scalable spatial transcriptomics analysis for various tissue sizes and adjustable resolutions..