Excited to share our new preprint: 'A Developmental Cell Atlas of the Human Thyroid Gland' on biorxiv.org/content/10.110…! We uncover the diversity of thyrocytes throughout lifespan, offering insights into #thyroid development in health & disease… 👇

I wonder what this means for scRNA-seq, especially cancer scRNA-seq? Looks super cool

Every once in a while you see a paper and you _don't even know what to think_ honestly. I mean wow. Is it an artefact or a major mechanism of inheritance would be one question I'd definitely like to know. P.S. I think height heritability is considered to be fully explained now.

Aside from the sheer facepalm value of this tweet, quote reposts are 🤌🤌🤌 - Kamala Cell reaction got me crying

Congrats to my friend and colleague Guosong Hong for his stunning and original discovery, published today in Science, on clearing tissues *in living animals* with a common food dye! The dye is tartrazine, used in Doritos! science.org/doi/10.1126/sc…

journals after ghosting you for 6 months

It really happened, didn't it. I wasn't sure that it would. Looks like PTM field is going to be mad for the next few years.

Pre-PhD: imposter syndrome Post-PhD: Dr Imposter Syndrome

every man in east london

Our team has been working on a pipeline to reliably detect bacterial reads in human RNA-seq data - incl. various single cell platforms and Visium. I will be presenting our way of doing this type of analysis at the Festival of Genomics (Jan 29-30th, 2025) in London. Please join!

Over the summer, I went to the very North of the Isle of Lewis on a field trip to map the geology there with a close friend of mine. The google street view car went past. We had a geological hammer. The following masterpiece, now on google street view, was the result

Just to be crystal clear, “I feel fine but my wife made me come in” has a positive predictive value for something being *really* fucking wrong that approaches 100%

University websites are like distant stars, when you look at them you see the scientists as they used to be many years ago

Out today in Nature: "The Human Cell Atlas"! In my commentary, I compare the cell atlas to early naturalists exploring South America. Researchers mining this cell atlas can now make big discoveries, just as the next naturalists then discovered evolution. nature.com/articles/d4158…

I am beyond excited to see our MEGA gut paper published in nature! 🌟 Over 5 years, 20+ datasets profiled cells of the human gut. We created a mega dataset spanning health & disease (~1.6M cells) as a reference to study inflammation. 🧵Follow along for your daily gut wisdom.

I honestly want to leave this damn app, and then something like this happens

Forever.

Top 5 advances in medicine this week (🧵) 1. Vitamin C modifies the amino acid, lysine, to form VitCyl-lysine This is a novel post-translational modification: it promotes immunity and (in mice!) boosts anti-PD1 immunotherapy to kill cancer Whether vitamin C can also boost

I didn't have much hope that we'd find genetic determinants of long-COVID, but after years of work, Vilma Lammi, Tomoko Nakanishi, Hugo Zeberg and Hanna M Ollila made it happen! nature.com/articles/s4158…

“One of the biggest tragedies I've observed in my professional life.” David R. Liu, winner of the Breakthrough in Life Sciences and professor at the Broad Institute and Harvard University, describes the cost of government cuts to science research at universities. Walter Isaacson