Ho pianto perché oggi va così. Ma questo è davvero un articolo bello e di cui si sente molto il bisogno. ilpost.it/2024/04/10/sei…

AI speeds up drug design for Parkinson’s by ten-fold: Researchers have harnessed the power of artificial intelligence to revolutionise the search for treatments. Vendruscolo Lab #Chemistry #Parkinsons #AI ch.cam.ac.uk/news/ai-speeds…

interfering with morphogen gradients is a challenge......! this is a step in that direction

An autoantibody signature predictive for multiple sclerosis | Nat Med nature.com/articles/s4159…

"the reliance on transcriptomics to define cell types comes with intellectual hazards." Wisdom from West Lab @ Duke 🙌 These snapshots miss the dynamics of plasticity (or other cell states). thetransmitter.org/defining-cell-…

«Nella Resistenza la donna fu presente ovunque: sul campo di battaglia come sul luogo di lavoro, nel chiuso della prigione come nella piazza o nell’intimità della casa». (Ada Prospero Marchesini Gobetti) Buon #25aprile , buona #festadellaliberazione #resistenza #antifascismo

In neurons, lysosomes transport certain mRNAs into axons, maintaining ribosomal and mitochondrial function in these synaptic hot spots. NIH ow.ly/pYHW50RpocO

Seizures exacerbate excitatory: inhibitory imbalance in Alzheimer’s disease and 5XFAD mice academic.oup.com/brain/article-…

De novo design of high-affinity single-domain antibodies biorxiv.org/content/10.110…

So great to see Moses in this pic. Wish I could be there to celebrate with you 🍾

Da oggi in libreria!

vagus nerve starring brain-immune axis the vagus and the soul "Animula vagula blandula Hospes comesque corporis Quae nunc abibis in loca? Pallidula rigida nudula Nec ut soles dabis iocos" (Historia Augusta) quoted in Marguerite Yourcenar's Memoires d'Hadrien

machine unlearning algorithms be inspired by how the brain forgets #neuroAI physiological forgetting Paul Frankland Sheena Josselyn ― William James, The Principles of Psychology (1890) “In the practical use of our intellect, forgetting is as important a function as recollecting.”

Dona il 5×1000 a EBRI - CF 97272740586 Possiamo sconfiggere le malattie neurodegenerative se a lottare siamo in tanti. Prendi parte alla ricerca, dona il 5×1000 a EBRI. ebri.it/dona-il-tuo-5x…

Our new paper "The landscape of cancer-rewired GPCR signaling axes" is out on Cell Genomics cell.com/cell-genomics/… Huge work by chakit arora and the bioinformatics group of Scuola Normale. Great collaboration with GutkindLab, Natoli IEO and other groups!

IUPHAR Rhea database reactome Marin Matic GutkindLab OmniPath Julio Saez-Rodriguez MINT database Luisa Bisceglia Francesco Carli Fondazione AIRC per la ricerca sul cancro Last but not least, we are humbled and grateful to Balaji Santhanam, Madison Sluter and Madan Babu M. Madan Babu for their great preview about our work. You can read it here: cell.com/cell-genomics/…

early finding (Capsoni et al (2012)) that "Pathogen Free Conditions Slow the Onset of Neurodegeneration in a Mouse Model of Nerve Growth Factor Deprivation doi 10.3233/JAD-2012-120427 Journal of Alzheimer's Disease, 31: 1-6

Our work on #Arc is out, such a peculiar protein showing a diverse amount of oligomerization depending on the specific location within dendritic spines. If you like to learn more follow Martina Damenti thread!

“Ho commesso un’infrazione alla prassi di protocollo del Quirinale, andando una seconda volta al medesimo evento, gli Europei di atletica. Ma vi assicuro che ne valeva la pena” 𝑆𝑒𝑟𝑔𝑖𝑜 𝑀𝑎𝑡𝑡𝑎𝑟𝑒𝑙𝑙𝑎 🇮🇹

A panel of eight plasma proteins can detect #parkinsonsdisease up to seven years before motor symptoms occur. UCL Uni Göttingen ow.ly/jCeO50SnwRF