Kudos to Joe Elmunzer & team for the publication of the much awaited SVI trial 🔥🔥 ✅ Indomethacin alone is inferior to Indomethacin + PD stent in prevention of post-ERCP pancreatitis ! ✅ Another take home for me: Rates of PEP > 11% in high risk pts Now in The Lancet

Endoscopic Tissue Sampling ▪️Esophagus ▪️Stomach ▪️Small intestine ▪️Colon ▪️Miscellaneous Here’s another version I compiled. Note: overall low quality of evidence for each recommendation, but this can be nice guidance for early endoscopists. #GITwitter

Resmetirom is a highly selective thyroid hormone receptor β (THR-β) agonist. Probably not on most people's short list of most-likely MoAs (mechanisms of action) 10 years ago, but here we are... Once again, translational science is hard. Elliot Tapper

Editor's Choice: Risk of delayed bleeding after colorectal endoscopic submucosal dissection: the Limoges Bleeding Score Find the article at: doi.org/10.1055/a-2189… Jérémie Albouys et al. Endoscopy 2024; 56: 110–118 DOI 10.1055/a-2189-0807

Currently, no pharmacotherapies are approved for nonalcoholic steatohepatitis. Resmetirom is an oral, liver-directed, THR-β–selective agonist in development for NASH. Research findings for the MAESTRO-NASH trial are summarized in a new Quick Take video. youtu.be/wwKhWt0pFh8

So this is pretty cool ... Using abatacept to prevent onset of rheumatoid arthritis in individuals at high risk high risk = antibodies to citrullinated protein antigens (ACPA), rheumatoid factor, and symptoms, such as inflammatory joint pain

🆕Finally, it's out! 🚨⏩⏩Published in Nature Communications our study on mucosal host-microbe interactions in association with clinical phenotypes in inflammatory bowel disease: nature.com/articles/s4146… WeersmaLab Shixian A 🧵below:

AXIOS Lumen Apposing Metal Stent (LAMS) for WOPN A 🧵for folks learning #advancedendoscopy 1. Perform endoscopy first ▶️measure GEJ (want to avoid placing LAMS in esophagus if possible), evaluate stomach/duodenum for extrinsic compression #GITwitter #MedEd ASGE GI Endoscopy

Thiopurine monotherapy is essentially no more in the updated ECCO Crohn’s guidelines 👏👏👏

ACG guidelines on the management of acute pancreatitis 🆕📍 journals.lww.com/ajg/fulltext/2…

Upadacitinib for Crohn's disease • data from Edinburgh and Exeter • n=93 with median 25w follow-up • effective in highly refractory cohort See 👇 for figures and link Frontline Gastro

jnmjournal.org/journal/view.h… Review on Evaluation & Management of Refractory #GERD with some nice algorithms that summarises the gist of the recent Lyon 2 Consensus How you evaluate GERD depends on 1⃣ Type of symptoms 2⃣ Whether GERD is proven #GITwitter

Breaking news: Live for #ESGEDays2024 Colorectal polypectomy & endoscopic mucosal resection ESGE Guideline. Hear lead author Monika Ferlitsch discussing in detail on Saturday, 13:30, Convention Hall 1A: Guideline session LGI. esge.com/colorectal-pol……...

New EASL Education #MASLD Guidelines released at #EASL2024 #EASLCongress in Milan. journal-of-hepatology.eu/article/S0168-…

Congratulations! Fantastic update 🤩 Relevant changes from 2019 ✅do not stop biologicals prior surgery (2019 was conditional) ❌no fibrin glue for perianal ✅IFX & ADA for perianal ❓VEDO, UST, RIS, UPA in perianal And much more relevant data! Definitely 👍