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biorxiv.org/cgi/content/sh…

ICGEB Official ICMR Department of Biotechnology DBT/WT India Alliance Emory Vaccine Center Nikhil Singla ICGEB, New Delhi Mehul Suthar Prashant Bajpai Vanshika Singh We discovered a broad and potent human mAb (002-S21F2) that neutralizes several live viral isolates of SARS-CoV-2 variants including Alpha, Beta, Gamma, Delta, and Omicron (BA.1 & BA.2) at very low IC50 ranging from 0.02 – 0.05 µg/ml Anamika

Excited to announce that our manuscript "Structural insights for neutralization of Omicron variants BA.1, 2, 4 and 5 by a broadly neutralizing Sars-CoV-2 antibody" got accepted to be published in Science Advances. A wonderful collaboration among labs around the world!

Our lab has characterized an antibody that neutralizes a broad array of COVID variants (from Wuhan to Omicron)...this could have exciting implications on therapeutics and vaccines against #COVID 💉🔬 (cc: Emory Research NIH Emory Department of Biochemistry) biorxiv.org/content/10.110…

biorxiv.org/content/10.110… Here is our preprint on the impact of the BA.2.75.2 and BQ.1.1 variants on neutralization of sera from bivalent mRNA boosted individuals. Bivalent vaccines are improving responses against BA.5. But BQ.1.1 and BA.2.75.2 are more evasive to neutralization.

Team headed by A. Sharma, K. Murali-Krishna, A. Chandele & E. Ortlund characterized 3 monoclonal antibodies generated from COVID-19 recovered individuals in India and present their cryo-EM structures with the bound spike protein ICGEB Official Emory School of Medicine doi.org/10.1016/j.str.…

Light chain of a public SARS-CoV-2 class-3 antibody modulates neutralization against Omicron dlvr.it/Sw3cl6

#CryoEM Any idea what this E.Coli contaminant might be?