Researchers in the Cheeseman lab have identified an important molecular switch that induces a distinct pattern of protein variant production during mitosis. #ResearchHighlights

Pavana Rotti, who studies the neurobiology of opioid use disorder, discusses her work-life balance as both a parent and a postdoc. wi.mit.edu/news/meet-whit… #WhiteheadPostdocProfiles

The unprecedented cuts that have taken place to research will cripple science in America. This affects ALL Americans, risking our collective health, safety, and national security. Please reach out to your local gov. Representatives and stress the importance of STEM in the USA!!

Trying to focus on the small positives given all the chaos. For example, today the Nguyen lab got our first package! Ready to do some kick ass science 💪

New preprint countdown! Mitochondria are cells within our cells. They need the same core activities - replication, transcription, translation. How do cells enable these diverse activities in both compartments? We uncover an unexpected strategy with ancient origins. Stay tuned!

🚀 Exciting news for early-career researchers! The new Max Planck #Postdoc Program offers a guaranteed contract of at least 3 years, targeted mentoring, and career workshops. Applications are open now! postdocprogram.mpg.de #ScienceCareer #PostdocProgram

My lab is hiring a research assistant to work on 3D genome architecture in frog embryos. Please spread the word! #xenopus #chromatin 🐸 🧬🔬 employment.ku.edu/jobs/staff/ass…

First official Nguyen Lab photo! Welcome to the team Molly and Michael! 🔬Check out what we are working on at Nguyenlab.org

Delighted to share our updated work, led by postdoctoral fellow Dr. Maria Campaña, published in Nature Communications: rdcu.be/em66g, PDGFRalpha/beta heterodimer activation negatively affects downstream ERK1/2 signaling and cellular proliferation

Optical Pooled Screening has transformed large-scale cell biology, but lacks robust end-to-end computational strategies to process these Tb-sized datasets. New from Di Bernardo et al (Matteo Di Bernardo): Brieflow. A game changer for OPS + new biological insights biorxiv.org/content/10.110…

Optical pooled screening is revolutionizing functional genomics by linking genetic perturbations to complex cellular phenotypes at unprecedented scale. But analyzing these massive datasets has been a major bottleneck - researchers face fragmented tools, multiple format

Setting up a lab has been no joke. Today, I'm stoked to have one more piece of my postdoc work out in the wild. Several more manuscripts to go, and I don't have a lot of time for a tweetorial today, but enjoy and happy to get any feedback on this story. biorxiv.org/content/10.110…

New pre-print! Ryan Kim et al distinguish the roles of the Spindle Assembly Checkpoint as a surveillance pathway only triggered by mitotic errors vs a mitotic timer that is required in every cell division. biorxiv.org/content/10.110…

1/ I'd like to share a major part of my postdoctoral work, co-mentored by Rudolf Jaenisch and Richard Young, and a major collaboration with Olivia Corradin Corradin Lab, all at Massachusetts Institute of Technology (MIT) MIT Biology and Whitehead Institute.

Debosmita Sardar, PhD, and Justin O’Hare, PhD, Assistant Professors in the Department of Pharmacology, have received Klingenstein Fellowships in Neuroscience, one of the nation’s most prestigious awards for early career scientists. Their high-risk, high-reward research explores

New preprint! We solve a mystery you didn't know existed. Mitotic cells lack new transcription but require ongoing translation. Interphase mRNA half life is only 2-4 hrs. So how do cells arrest in mitosis for hours without depleting their transcriptomes? biorxiv.org/content/10.110…

Really nice write-up on mine and Justin O'Hare research that was recently awarded the highly competitive @KlingensteinOrg neuroscience awards. Thank you CU School of Medicine for the shout out! And CU Pharmacology for providing such an exciting scientific environment for #newPI