This collaborative study with my partner in crime (Matthias Stadtfeld) is the result of very hard-work and resilience of two amazing postdocs Boaz Aronson and Laurianne Scourzic and help of many others, including Meelad Dawlaty, Hynek Wichterle, Thomas Vierbuchen and Aristotelis Tsirigos!

Just like my pumpkin carving, better (a week) late than never to tweet! Our work with Effie Apostolou Boaz Aronson and Matthias Stadtfeld on the role of the fascinating TETs/DNMTs in genomic imprinting is now out in Developmental Cell: cell.com/developmental-…. Many thanks to all involved !

A wonderful paper from the twitter-less Nefeli Slavi @LadyGlaucoma and the @drcarolmason lab, linking gene expression in the CMZ with the establishment of the binocular circuit and depth perception. biorxiv.org/content/10.110…

NSD2 E1099K drives relapse in pediatric acute lymphoblastic leukemia by disrupting 3D chromatin organization NYU Grossman School of Medicine biorxiv.org/content/10.110…

Very excited to present our latest work with Jimin Tan and Bo Xia: using machine learning to predict cell type-specific chromatin architecture and enable in silico perturbation studies! NYU Grossman School of Medicine Perlmutter Cancer Center at NYU Langone Health biorxiv.org/content/10.110…

Our new study: C.Origami predicts cell type-specific 3D chromatin structures 🧬 and enables genome wide screening for crucial factors. It has been an honor working with Bo Xia and Aristotelis Tsirigos in this exciting project! Check out our website and a live demo! tanjimin.github.io/c.origami-intr…

New preprint from the lab! Led by @IMPRS_GS PhD students Shu Zhang and Nadine Ubelmesser and supported by Mariano Barbieri for modeling, we found selective dependency of enhancer-promoter loops on RNAPII using #MicroC. Our work assigns RNAPs with a clear role in #3Dgenome folding

#postdoc position available in my lab! Exciting opportunity to work on the role of #ncRNAs and #ChromatinArchitecture in #StemCells IIT. This position is fully supported by the ECF fellowship from the Human Technopole and will be based in Genova (Italy). nature.com/naturecareers/…

Slavi et al. Neuron CyclinD2-mediated regulation of neurogenic output from the retinal cil... sciencedirect.com/science/articl…. Extremely proud to have worked in this seminal study led by Nefeli Slavi. Congratulations to all the participants. #AcademicTwitter

C.Origami, a machine learning model for cell type-specific chromatin architecture prediction and discovery of putative regulatory elements! Developed by our student Jimin Tan in collaboration with Bo Xia. Nature Biotechnology 4DNucleome EpigeneticsChromatin epigenetics_papers

Our C.Origami paper is accepted at Nature Biotechnology. Special thanks to Bo Xia, Aristotelis Tsirigos and all my collaborators for their invaluable guidance and support along the way. It has been an amazing journey!

Happy to see our own Varvara Paraskevopoulou representing blood cancer at Fusion Conferences "Animal Models of Cancer"! Dont forget: Leukemia is a cancer and it has it's microenvironment 😀! Thanks Kevin Haigis Lab & Julien Sage for inviting Varvara! #AifantisLab NYU GSOM Pathology #CancerResearch

GoT-ChA! I am thrilled to announce that our paper "Mapping Genotypes to Chromatin Accessibility Profiles in Single Cells" is now out in nature !! 👩‍🔬👨‍🔬🧬If you want to link somatic mutations to epigenetic changes directly in patient samples: nature.com/articles/s4158… 👇🧵

🚀🚀🚀 Feeling beyond grateful and thrilled to share that our lab has been awarded the FIS grant from the Italian Ministry of Education! 📢 To all chromatin lovers: our lab will soon be opening up several positions! Contact me directly if interested! opentalk.iit.it/le-ricercatric…

Cohesin is essential for maintaining structural loops but less so for regulatory loops and transcription. Is cohesin actually required for the establishment of loops and transcriptional activation?🧵bit.ly/4hXremH