Excited to share our study on the treatment effect and underlying mechanism using a triple therapy of VEGF+PDL1+CTLA4 blockade in CCA, published today in Immunity👨‍🔬🥳 Article: authors.elsevier.com/c/1km4D3qNrU-h… A brief summary of the exciting science from @TimGreten lab below: (1/6)

🎯 Alba Jiménez presenting a great collaboration between the labs of NIH Hager, Liège Dequiedt, Juan F. Recio Kaustubh Wagh Greg Fettweis Diana Stavreva Andrea Alegre and more collaborators & our lab IBUB-UB Biochemistry & Molecular Biomedicine UB at the Barcelona BSC Computational meeting 🧩

🎯 We have this week an intensive workshop on protein-protein interactions programs IBUB-UB Biochemistry & Molecular Biomedicine UB lead by awesome Alba Jiménez-Panizo now JdC at Juan F. Recio's lab in Logroño 🧩🚀

Sharing out recent work on GR in the etiopathogeny of atopic dermatitis at the French-Spanish NR meeting

🎯 We are so thrilled our new paper Nucleic Acids Res is out! IBUB-UB Biochemistry & Molecular Biomedicine UB Fantastic collab with the labs of Gordon Hager NIH & Franck Dequiedt Liège. Huge thanks to Greg Fettweiss, Kaustub Wagh, Diana Stavreva & Alba Jiménez, Andrea Alegre & teams 🎉🥳 academic.oup.com/nar/article/53…

Very happy to share our latest research, published in Nucleic Acids Research! This work was a fantastic team effort from the Hager lab, the Estebanez lab, the Fernandez lab, and the Dequiedt lab. academic.oup.com/nar/article/53…

Our latest article made the cover Nucleic Acids Res! Read about how transcription factors guide NIPBL/MAU2 to enhancers here: doi.org/10.1093/nar/gk…

#ArticleOfTheMonth I June 2025 📝Transcription factors form a ternary complex with NIPBL/MAU2 to localize cohesin at enhancers 🔗Access the full article here 👉 goo.su/DQmuRBz

Dear colleagues, Argentinean science is dying. I am not kidding. The government has halted National funding, they are firing people and shrinking our institutions. Please help us spread the word. youtu.be/76tYd-QRIfI?fe…

Happy to share that our latest research study is out now Genome Research Androgen receptor-mediated assisted loading of the glucocorticoid receptor modulates transcriptional responses in prostate cancer cells genome.cshlp.org/content/early/…

📢 Another bioRxiv on GR from our lab in collaboration with Pablo Fuentes-Prior Gordon Hager NIH Diego Presman Paloma Perez lab IBV-CSIC #FRecio & the amazing Andrea Alegre Martí Alba Jiménez-Panizo, PhD Agustina Lafuente #InésMontoya & montse abella 🚀 doi: doi.org/10.1101/2024.1… Biochemistry & Molecular Biomedicine UB IBUB-UB Facultat de Biologia UB

📢 Grateful talented Inés Montoya was selected to FEBS Functional Genomics in Spetses Greece She will show our work on bile acids binding to GR that modulate activity, oligomerization & chromatin binding 🎯 Thrilled to collab with Fuentes, Hager, Recio, Presman, Goldstein Labs

📢 Happy we had a big turnout of interested colleagues at the SBE 2025 poster session. Glucocorticoid (GR) multimerization; GR ternary complex with Nipbl+Mau2 & GR modulation by bile acids posters triggered exciting questions 📌

🎯 Thrilled to visit my 2nd home San Francisco! Excited to talk at #ENDO20 thiSaturday with montse abella Andrea Alegre Martí our research on #nuclearreceptors with Pablo Fuentes-Prior Alba Jiménez-Panizo, PhD Diego Presman #GordonLHager #JFRecio #JRubio María Nuria Peralta Moreno & meet former Fletterick Lab ✨️

🎯 Join me & part of my team today 13:45-15:15 at the ENDO2025 Meeting at Room 303 Session OR04 - Receptor Biology and Signal Transduction - Steroid Receptors in Action to discuss Androgen Receptor Multimerization Modulators. New Drugs against Prostate Cancer with novel MOA 💎⚡️

#ENDO2025 Congress San Francisco USA 🌉 Presenting our work on Structure of Nuclear Receptors done Biochemistry & Molecular Biomedicine UB Facultat de Biologia UB Pablo Fuentes-Prior Andrea Alegre Martí Alba Jiménez-Panizo, PhD

🎯 These 5 years have been amazing for our lab, motivated & cohesioned lab blessed with outstanding collaborators around the world. Discovery & synergies with smart, synchronized scientists & better people on our wavelength is fantastic. That is what I love about Science✨️🚀

We are heartbroken to learn about the passing away of David Mangelsdorf. Only a few weeks ago he was delivering in San Francisco #ENDO2025 an amazing and amusing talk together with Steve Kliewer. The Spanish Nuclear Receptor Nurcamein community is mourning his loss.

🎯 Read the Protein Science paper lead by Alireza Mashaghi with Laurens Heling, Vahid Sheihhassani et al about polyglutamine expansion induced dynamic misfolding of the androgen receptor also in colab with Iain McEwan 🎉

🎯 Check Journal of Physical Chemistry paper lead by Alireza Mashaghi on phosphorylation-regulated conformational diversity and topological dynamics of an intrinsically disordered nuclear receptor with Vasily Akulov as first author in collab with John van Noort and Alba Jiménez-Panizo, PhD 🎉