1/ 8 Books for you to learn bioinformatics🧵

pubs.acs.org/doi/10.1021/ja…

Tim Coorens Looking for a postdoc opportunity? Tim's group is currently recruiting postdocs as part of the EMBL-EBI Wellcome Sanger Institute (ESPOD) postdoctoral fellowships ebi.ac.uk/research/postd…

Spliceosome Dynamics During splicing, stepwise assembly is one principle by which spliceosomes on the one hand ensure the faithful recognition of splice sites and on the other hand become susceptible to regulatory inputs to implement alternative splicing.

Published on JCIM & JCTC Journals : pubs.acs.org/doi/10.1021/ac…

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Discuss single-molecule science with world-renowned Prof. @Taekjip Ha (Harvard University )! Join the upcoming Nature webinar to learn how dynamic single-molecule tools reveal new mechanisms behind nucleosome mobilization and transcriptional control! Registrations are now open:

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In the latest issue! Small RNAs are modified with N-glycans and displayed on the surface of living cells dlvr.it/TMS2Dq

Neutrons, despite being electrically neutral, can diffract in crystals because they have a magnetic moment and interact with nuclei via the strong force, revealing nuclear positions directly.

A multichaperone condensate enhances protein folding in the endoplasmic reticulum: nature.com/articles/s4155…

The intrinsically disordered regions of organellophagy receptors are interchangeable and control organelle fragmentation, ER-phagy and mitophagy flux: nature.com/articles/s4155…

Structural analyses define the molecular basis of clusterin chaperone function: nature.com/articles/s4159…

Hopes are high that AI can accelerate scientific discovery. Let's balance this hope with a reality check. 🧵

A Bioinformatician's UNIX Toolbox I know I am still old-school :) lh3lh3.users.sourceforge.net/biounix.shtml

Glycopolymers stabilize protein folding and protein-protein interactions via enthalpic interactions biorxiv.org/content/10.110… #biorxiv_biophys

Recruitment is now open for the EMBL-EBI–Sanger Postdoctoral (ESPOD) Programme. ESPOD builds on the collaborative relationship between EMBL-EBI and Wellcome Sanger Institute, offering projects that combine experimental and computational approaches. ebi.ac.uk/research/postd… #postdocjob

Reaching the full potential of cryo-EM reconstructions with molecular dynamics simulations at 310 K: Actin filaments as an example biorxiv.org/content/10.110… #biorxiv_biophys

Small molecule dysregulation of ClpP activity via bidirectional allosteric pathways: Structure cell.com/structure/full…

Inspired by natural molecular glues, drug hunters are chasing protein–protein interactions with next-gen small molecules tuned for enhanced tissue specificity and reduced toxicity nature.com/articles/s4158… rdcu.be/eAC91