CAR-T for Glioblastoma: Penn Medicine's Dr. Donald O'Rourke describes advances being seen today in using CAR-T against glioblastoma. Penn Medicine - Abramson Cancer Center Full video: biotechtv.com/post/penn-medi…

US drug regulators dropped a bombshell in November 2023 when they announced an investigation into one of the most celebrated cancer treatments to emerge in decades go.nature.com/4acmi90

Congratulations to all Penn Engineering doctoral candidates graduating today! #PennEngineeringProud

How to avoid burnout Credit: Victoria Repa #PhD #PhDlife #academics #AcademicChatter #AcademicTwitter #Postdocs #Research #Science

Integrative molecular and spatial analysis reveals evolutionary dynamics and tumor-immune interplay of in situ and invasive acral melanoma dlvr.it/T85wPF

The temporal progression of lung immune remodeling during breast cancer metastasis dlvr.it/T8B154

Excited for our pub. in Nature Communications, Human Shu complex promotes RAD51 activity by modulating RPA dynamics on ssDNA, Congrats to ⁦@science_SRH⁩ ⁦Ben Van Houten⁩ ⁦Chelsea⁩ ⁦Maria Spies, PhD (she/her)⁩ ⁦Matt Schaich⁩ et al nature.com/articles/s4146…

Get to know soon-to-be geography MS graduate Olamiposi "Caleb" Fagunloye Olamiposi Caleb Fagunloye 🛰️📡🌍 in our November GEOS spotlight below! geosciences.gsu.edu/2024/11/01/geo…

Liquid biopsy: a promising tool for cancer screening, but sensitivity for early-stage detection remains a challenge. Innovation is key to improving outcomes. Critical Reviews in Oncology Hematology (CROH) The Journal of Liquid Biopsy #LiquidBiopsy #Oncology #PrecisionMedicine #ISLB24 Christian Rolfo ELO International Society of Liquid Biopsy

So incredibly proud of Adeola for successfully defending his dissertation last week. Our understanding of the Shu complex role in finding replicative DNA damage has now been revealed ….stay tuned.

Kara Bernstein Congratulations to you and Adeola on at outstanding thesis defense and dissertation!

Enjoyed a very fun and scientifically inspiring Biochemistry and Biophysics Retreat in the Poconos. ⁦BBCB Graduate Group⁩ UPenn Dept of Biochem & Biophys⁩

NEW: Today, I’m releasing a Surgeon General’s Advisory on the causal link between alcohol consumption and increased cancer risk. Alcohol is the 3rd leading preventable cause of cancer in the U.S., contributing to about 100,000 cancer cases and 20,000 cancer deaths each year.

Today "a milestone in the evolution of personalized therapies for rare & ultra-rare inborn errors of metabolism" —the 1st human to undergo custom genome editing —outgrowth of decades of NIH funded research nejm.org/doi/full/10.10… nejm.org/doi/full/10.10… NEJM

A baby named KJ, who was born with a rare genetic disorder – CPS1 deficiency – is healed thanks to doctors at the Children's Hospital who administered the world’s first personalized gene-editing treatment. The research team used base editing, a gene-editing method invented by HHMI

1/10 Today in Science Magazine in collaboration with liugroup we report the development of a laboratory-evolved CRISPR-associated transposase (evoCAST) that supports therapeutically relevant levels of RNA-programmable gene insertion in human cells. drive.google.com/file/d/1I-UbCR…

An innovative genome-editing tool promises to do what original CRISPR systems have struggled to achieve: insert entire genes, precisely and efficiently, into human DNA go.nature.com/430GeeB