A two month timelapse of the first Multimodal Optical Scope with Adaptive Imaging Correction (MOSAIC) build by a hard-working team at the ABC UC Berkeley UC Berkeley MCB @rxist525 Cyna Shirazinejad CZI Science

Next time you are writing the microscopy methods section for a paper, consider encapsulating your configuration in an FPbase microscope as Jeeyun Chung et al did: sciencedirect.com/science/articl… Wouldn't you rather evaluate a microscopy setup like this? fpbase.org/microscope/H6Z…

Big congrats to Dong Li and their new paper in Nature Methods! 👏👏👏nature.com/articles/s4159… If you want to see what I think is the best scientific cat figure since Schrödinger's read our News & Views on the paper nature.com/articles/s4159…

Imaging scientists are essential to accelerating biomedicine. 🔬 Thank you to our grantees and partners for a productive virtual convening this week. We’re grateful for your work! #ImagingTheFuture

Origin of wiring specificity in an olfactory map: dendrite targeting of projection neurons biorxiv.org/cgi/content/sh… #bioRxiv

Nanoscale volumetric fluorescence imaging via photochemical sectioning biorxiv.org/cgi/content/sh… #bioRxiv

(1/x) We are excited to introduce VIPS (Volumetric Imaging of biological specimens via Photochemical Sectioning) in our preprint! VIPS uses a light-based process called “photochemical sectioning” to achieve petabyte-scale high/super-resolution imaging: biorxiv.org/content/10.110…

Neural space-time model (NSTM) was published this week in Nature Methods ! Check it out: nature.com/articles/s4159… It is a flexible and robust model to tackle motion blur and improve temporal resolution in computational cameras/microscopes.🧵👇

Out today from Ruan, Betzig, Upadhyayula and colleagues! PetaKit5D offers versatile processing workflows for petabyte-scale light sheet microscopy data. nature.com/articles/s4159…

Almost everyone in microscopy (especially LSFM) talks about data deluge, but the tools haven't kept apace with the problems. Check out PetaKit5D for processing and analyzing your huge datasets!

Unlocking the potential to image petabyte-scale datasets 😵‍💫! From #CZBiohubSF Investigator Gokul Upadhyayula and co-corresponding authors & @BerkeleyMCB colleagues Xiongtao Ruan and Eric Betzig.

The MOSAIC reconfigurable microscope by Eric Betzig et al is finally out! MOSAIC integrates multiple advanced imaging techniques including light-sheet, label-free, super-resolution, and multi-photon, all equipped with adaptive optics: biorxiv.org/content/10.110…

Finally here! Our preprint on the MOSAIC, a multimodal adaptive optical microscope enabling non‑invasive in‑vivo imaging from molecules to organisms, is out. biorxiv.org/content/10.110… Eric Betzig Legant lab

1/ Better late than never, here’s a long thread of threads summarizing our MOSAIC preprint. If you’re curious about the process by which a new microscope is conceived and brought into the world, this is the thread for you. If you’ve come for eye candy, there’s plenty of that too