Perfect day at Mary Lyon Centre at MRC Harwell for the practical part of our Mouse Models of mtDNA Disease course. Great programme ahead incl Seahorse XF analysis w Dr Micol Falabella, and pyrosequencing workshop w Stewart Lab, Mitophile & Dr Pavel Nash.

MRC National Mouse Genetics Network London Mitochondrial Centre Carlo Viscomi Minczuk Lab

Data handling is a crucial part of our work in the use of complex animal models to better understand human disease.

We will be working with the recently funded People in Data project on training the next generation of data professionals.

We're #hiring a Molecular Biologist and Senior Molecular Biologist to join our genome engineering team. Their work will span genome editing of the mouse genome and validation of engineered alleles.

Apply by 19th May

Please share!

mrc.tal.net/vx/lang-en-GB/…

Interested in using degron tagging to study the function of your favourite protein in genetically engineered mouse models? Check out our review covering recent work in this area: doi.org/10.1242/dmm.05…

First session of our Mouse Models of mtDNA Disease course kicked off with Robert Pitceathly & Carlo Viscomi giving an overview of mito diseases, genetics & models. Welcome to everyone who's travelled to join us!

Mary Lyon Centre at MRC Harwell MRC National Mouse Genetics Network Cambridge Clinical Mitochondrial Research Group Stewart Lab, Mitophile London Mitochondrial Centre

Thrilled our ‘team science’ TUBB4B work is out in Science Magazine led by Daniel Dodd MRC_HGU & Institut Imagine colleagues on how #RareDisease informs on fundamental biology- the ‘tubulin code’ & microtubule diversity within a cell & across tissues! science.org/doi/10.1126/sc… A 🧵/1

Two new translational research centres for rare diseases funded by LifeArc will be co-led by Profs Prof Michael Hanna, Robert Pitceathly & Hannah Mitchison UCL Queen Square Institute of Neurology UCL Great Ormond Street Institute of Child Health. They aim to improve access to diagnostics, treatments and potentially cures.
ucl.ac.uk/news/2024/apr/…

Genetically engineered mouse models of cancer provide vital insight to help drive the next generation of cancer treatments. Check out my piece for Open Access Government @mrc_nmgn_cancer Cancer Research UK in Scotland Asthma + Lung UK 👇
doi.org/10.56367/OAG-0…

Thank you all for the honour -- such a pleasure to work with all of you and be part of your success 💕 Thanks especially to my amazing team!

You are invited to an exciting day of talks and discussions centred around 'Resources and Funding Opportunities in Rare Disease' here at Advance at MRC Harwell on 6th June.

Register by 27th May:

docs.google.com/forms/d/e/1FAI…

#RareDiseases

Registration still open for our free course on 'Models of Mitochondrial DNA Disease' coming up on 29th April! Sign up here: forms.gle/xAywfeXJ3rNFZa…

Ft talks by Robert Pitceathly Stewart Lab, Mitophile Carlo Viscomi
Minczuk Lab Mary Lyon Centre at MRC Harwell

MRC National Mouse Genetics Network

Read more about one of the fantastic projects that our MRC NMGN Cancer Cluster Cluster members Sid Philip Dunne Simon Leedham Owen Sansom 🏳️‍🌈 and collaborators have been working on👇

MRC National Mouse Genetics Network Thanks for highlighting our work: nature.com/articles/s4158…

Great research led by Sid across Belfast The Patrick G Johnston Centre for Cancer Research , Glasgow CRUK Scotland Inst and in collaboration with Viktor H Koelzer Simon Leedham, the wider MRC NMGN Cancer Cluster & our ACRCelerate Science and Innovation at Cancer Research UK EarlyDetection programmes!

Don't forget, there is still time to register for the Beatson International Cancer Conference!

👇Check out what delegates had to say about last year's event

📅Book your place by 31 May: crukscotlandinstitute.ac.uk/events/beatson…

#BICC2024

Using a pathway-level approach to tumour categorisation, Philip Dunne's group and collaborators have identified a previously overlooked subtype of colorectal cancer with a very poor prognosis:
nmgn.mrc.ukri.org/news/categoris…

Congratulations to Professor Gopal Sapkota who has just received the prestigious Biochemical Society 2025 Industry and Academic Collaboration Award ppu.mrc.ac.uk/news/gopal-sap… #BiochemAwards Biochemical Society

Thanks Biochemical Society for recognising the hard work of present and past Sapkota Lab team members & our industrial partners. Very lucky to have excellent support, exceptional research environment and outstanding colleagues in MRC PPU, UoD Life Sciences and University of Dundee. Delighted!

🚨Early bird registration closing soon🚨

Register now for our 25th Beatson International Cancer Conference at the CRUK Scotland Institute - 'Cancer Models: from Cages to Clinic'

📅Monday 8th - Thursday 11th July 2024

🔗Find out more and register here: crukscotlandinstitute.ac.uk/events/beatson…

The MLC’s Molecular and Cellular Biology team, led by Lydia Teboul, have piloted how Oxford @Nanopore Technology long-read sequencing allows fast and robust analysis of genome-editing experiments:
har.mrc.ac.uk/news/long-read…

Daniel J. Murphy, Professor of Lung Cancer & Mesothelioma at the University of Glasgow, School of Cancer Sciences, discusses opportunities for improving #cancer research and care through the use of #genetically engineered #mouse models

bit.ly/3Vrz1Ri