We are delighted to announce one of our Business Engagement Fund projects. This collaboration between CRUK Scotland Inst and Oxford Drug Design will use #geneticallyengineered #mousemodels to validate new approaches to #cancertherapy nmgn.mrc.ukri.org/news/oxford-dr…

⌛️Abstract deadline approaching!

📅Just two weeks left to submit your abstract for the Beatson International Cancer Conference 2024 'Cancer Models: from Cages to Clinic'

👉Find out more: crukscotlandinstitute.ac.uk/events/beatson…

The first of what will be many senior author papers from a future leader in cancer research

👇 check it out and RT.. and make sure to follow Cassie for many more updates on this and other important research over the coming months.

The MRS is pleased to announce that registration for the 20th Biennial Meeting in London (23-25 June 2024) is now open here | → metastasis-research.org/2023/09/20/mrs… ← | Early Bird Registration is available until 31st March 2024 | MRS Members - keep an eye on your inboxes for more info.

Join us for the 25th Anniversary Beatson International Cancer Conference 2024! #BICC2024
'Cancer Models: from Cages to Clinic'

📅8th - 11th July

📍CRUK Scotland Inst, Glasgow, UK

🔗Register by 31st May: crukscotlandinstitute.ac.uk/events/beatson…

Terrific to see the mouse we made to examine the cancer causing potential of modestly elevated MYC expression being used successfully by other research labs! Mouse is available through Jaxmice: RRID:IMSR_JAX:033805 MRC NMGN Cancer Cluster

Brilliant talk today by Karen Blyth, co-lead of the MRC NMGN Cancer Cluster Cluster, at #DMMgenetics in Edinburgh, highlighting the need to develop better models to understand and treat human cancer and detailing some of our cluster’s work👍

Our 5-day Mouse Models for Human Disease Workshop brings together a team of experienced mouse geneticists and invited speakers to provide ECR attendees with a comprehensive course in everything mouse genetics

Note: 31st May application deadline!

har.mrc.ac.uk/training/cours…

One of our ECRs, Dale Watt, is presenting a poster highlighting some of the MRC NMGN Cancer Cluster Cluster work at #DMMgenetics in Edinburgh today 👏

Day 2 of #DMMgenetics brings more incredible talks and more Network’s involvement with Microbiome Cluster, MRC NMGN Cancer Cluster, MRC MitoCluster and MRC NMGN Haem Cluster. Royal Society of Edinburgh The Company of Biologists

Xiao Fu and Jen Morton 🏴󠁧󠁢󠁳󠁣󠁴󠁿🇺🇦 are looking for feedback on their project summary: Integrating computational and experimental approaches to improve treatment strategies for people with pancreatic cancer

👇Find out more and how to get involved below👇
pancreaticcancer.org.uk/get-involved-i…

The Network and Mary Lyon Centre at MRC Harwell taking centre stage with MRC NMGN Cancer Cluster, MRC NMGN Haem Cluster, MRC NMGN Congenital Anomalies and MRC MitoCluster representatives either chairing or speaking at today’s #DMMgenetics sessions.

Our own David contributing to the debate #BOARD24

#BOARD24 means a lot to us and our work to improve welfare and openness in animal research is an ongoing process.S.Wells worked on the standardisation of light conditions across facilities due to their effect on biology and welfare of the animals.har.mrc.ac.uk/news/shining-a…

For this week’s #FluorescenceFriday here is Grem1 ISH. Healthy tissue (left) it is confined to the trophocytes, HMPS pre-cancers (right) it is red hot in the epithelium 🔥🔥! Check out our latest pre-print below! #CancerResearch #preCancer

🔥🔥Pre-print alert!! GREMLINS are wreaking havoc on intestinal tissue!! Thankfully we have found a solution...

'GREMLIN1 disrupts intestinal epithelial-mesenchymal crosstalk to induce a wnt-dependent ectopic stem cell niche via stromal remodelling'
🧵

biorxiv.org/content/10.110…

Pleased to present latest lab preprint showing how pathological disruption of intestinal BMP gradients gives rise to ectopic stem cell niches through stromal remodelling.
biorxiv.org/cgi/content/sh…

The first invited talk of the afternoon is from Owen Sansom 🏳️‍🌈 of CRUK Scotland Inst UofG Cancer Sciences University of Glasgow on Wnt pathway mutations in colon and liver cancer.

#WntUK2024

Interested in using degron tagging to study the function of your favourite protein in genetically engineered mouse models? Check out our review covering recent work in this area: doi.org/10.1242/dmm.05…

For #BowelCancer AwarenessMonth , we'd like to give a shout-out to S:CORT, an Medical Research Council and Science and Innovation at Cancer Research UK funded UK-wide team seeking to apply novel technologies to improve and tailor the treatment of #ColorectalCancer ( #BowelCancer ) patients. 💪

cancer.ox.ac.uk/research/netwo…