Cool new work from Dr. Tyler Bell et al (inc Drs Franz, Kelsey R. Thomas Williams Lisa T Eyler Lerman Christine Fennema-Notestine Panizzon Jeremy Elman Kremen) Elevated CRP in Older Men With Chronic #Pain: Association With Plasma #Amyloid Levels and #Hippocampal Volume academic.oup.com/biomedgerontol…

Our paper hot off the press in Alzheimer's & Dementia Journals shows APOE4 carriers have blood-brain barrier breakdown even *before* amyloid accumulation or cognitive impairment, which correlates with microstructural damage. alz-journals.onlinelibrary.wiley.com/doi/10.1002/al… #Alzheimers #APOE #bloodbrainbarrier #dementia

Must-watch: Michelle Obama makes powerful case for why men should care about reproductive freedom

Women across America are dying because Republican states have banned abortion. No exceptions. If Republicans win in November, they've said they'll pass a national abortion ban. This video shows what will happen in every state. #MAGAAbortionBan

Seems like the exodus may be real this time. Jana Manning.bsky.social.

New article describing a regional parcellation scheme of abnormal white matter developed using #VETSA data!

Please RT or pass along to anyone looking for postdoc positions! Ample opportunity to pursue new and existing interests and gain training across multiple areas. This will include causal modeling of potentially modifiable risk factors of AD.

Preprint: Using 400k memory tests & 15k brain MRIs, we find no evidence that education enhances cognitive reserve. Edu linearly related to better mem, but not less brain or cogn decline, or more tolerance to atrophy 🧵LCBC - UiO Lifebrain @UiO_LifeSci medrxiv.org/content/10.110…

Great work led by McKenna Williams! I am particularly proud of Table 2, shown in McKenna's thread below. We hope that this is helpful in thinking about how different models can or cannot test different aspects of resilience.

‼️PhD Position now available in my lab‼️ Do you like: * Neurodegenerative disease? * Neuroimaging and/or multi-omics? * AI and data-driven life science? Want to work with RikOssenkoppele Alexandra Young and Laura Wisse? Apply here: lu.varbi.com/what:job/jobID… Please rt/share 🙏

I am so very proud announce my lab's first preprint!! Caly Yu Xiao (肖燏) delves into the mechanisms driving tau distribution: * Tau sequence driven by connectivity dynamics * Tau load driven by local factors Check out her thread below, or the preprint here! biorxiv.org/content/10.110…

Excited to share my new K01 work to understand chronic pain as an AD risk factor - a collaboration of the Vietnam Era Twin Study of Aging, The Panizzon Lab, and investigators for the Rush University System for Health ROSMAP data. doi.org/10.1093/brainc…

Our most important paper, out now! A massive international collaboration, led by Alexis Moscoso Rial, featuring over 6500 visually assessed tau PET scans covering the #Alzheimers spectrum! Thank you very much to the numerous contributors and collaborators who made this gem possible.

‼️Alert‼️Massive open dataset release!! The world’s largest proteomics dataset for neurodegenerative disease, including: * 250M+ protein measurements * 35,000 biosamples * 23 contributing cohorts * +50 harmonized clinical variables * AD / PD / FTD / ALS / Normal Aging 1/

🚨 Important work by Dr. Tyler Bell et al just out in J Int Neuropsychol Soc 1/🧵 cambridge.org/core/journals/…

Excited to share my new study with the Vietnam Era Twin Study of Aging team (Jeremy Elman The Panizzon Lab) published in #JINS showing that moderate-to-severe chronic pain and opioid use are independently related to risk of mild cognitive impairment. tinyurl.com/y88k5z4j UC San Diego