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aacrjournals.org/clincancerres/… Beautiful work Annapaola! An important contribution to our understanding of the effects of chemo and anti-PD1 immunotherapy on the immune response Annapaola Mariniello

Are computational biologists the drivers of research? 7 years ago I co-wrote an editorial about how computational biologists are no longer just supportive, but are now running the show. Today I would write how every biologist should also be computational. genomebiology.biomedcentral.com/articles/10.11…

Very happy to share our latest pre-print studying T cell dynamics in multiple myeloma disease evolution 🧵1/10. medrxiv.org/content/10.110…

Recruiting a PhD student in computational cancer immunology! Surgery and Cancer Working on understanding the immune response to placental cancers: ~75% are cured with anti-PD1 therapy. Lots of cool questions to work on. findaphd.com/phds/project/m…

#ELCC25 De-escalation clinical trials in NSCLC Impassioned presentation of the key trials, that can save pt’s time, toxicity, & ensure healthcare system sustainability - PULSE 🇫🇷 - Osi-Save 🇳🇱 - REFINE-Lung 🇬🇧 Benjamin Besse, best in the business ESMO - Eur. Oncology OncoAlert #LCSM

Interim analysis of REFINE-Lung is complete: reduced frequency 12-weekly pembro for NSCLC was not less effective than 6-weekly control. 6, 9, 12, 15 and 18-weekly arms are now open! Surgery and Cancer. Looking forwards to working with you Jarushka Naidoo

Also, many thanks to EORTC head and neck group for a stimulating discussion! If immunotherapy de-escalation works in one cancer type...should we apply this lesson across or the board, or will we need multiple trials?