Edwin Posadas, MD (@edwinposadasmd) 's Twitter Profile
Edwin Posadas, MD

@edwinposadasmd

Director,Cancer Therapeutics Program; Medical Director, Center for Uro-Oncology Research Excellence (CURE) - Cedars-Sinai-Cancer

ID: 1373710832

linkhttp://bit.ly/2e1QOte calendar_today23-04-2013 03:33:34

656 Tweet

610 Takipçi

192 Takip Edilen

Sumanta K. Pal, MD, FASCO (@montypal) 's Twitter Profile Photo

Always impressed w the CAR-T IITs my boss Tanya Dorff City of Hope has done in the #prostatecancer space. Tons of interest in her poster at the #ASCO23 GU poster session - it will be highlighted in the poster discussion today!

Always impressed w the CAR-T IITs my boss <a href="/TDorffOnc/">Tanya Dorff</a> <a href="/cityofhope/">City of Hope</a> has done in the #prostatecancer space. Tons of interest in her poster at the #ASCO23 GU poster session - it will be highlighted in the poster discussion today!
Neeraj Agarwal, MD, FASCO (@neerajaiims) 's Twitter Profile Photo

Breaking news👉#ASCO2023 ASCO Dr. #KarimFizazi presents the First results from all HRR positive 1st line mCRPC #ProstateCancer patients (n=399)from our phase 3 TALAPRO-2 trial👉Talazoparib + Enza significantly improves rPFS vs Enza (HR 0.45), OS trending well👇OncoAlert

Breaking news👉#ASCO2023 <a href="/ASCO/">ASCO</a> Dr. #KarimFizazi presents the First results from all HRR positive 1st line mCRPC #ProstateCancer patients (n=399)from our phase 3 TALAPRO-2 trial👉Talazoparib + Enza significantly improves rPFS vs Enza (HR 0.45), OS trending well👇<a href="/OncoAlert/">OncoAlert</a>
Edwin Posadas, MD (@edwinposadasmd) 's Twitter Profile Photo

Exciting to see rational combinations of 177Lu-PSMA with biological response modifiers. Important to see we can move the mark but we still need to optimize the biology. Timing is important. #ASCO23

Exciting to see rational combinations of 177Lu-PSMA with biological response modifiers. Important to see we can move the mark but we still need to optimize the biology. Timing is important. #ASCO23
Ravi A Madan M.D. (@dr_ravimadan) 's Twitter Profile Photo

Congrats to the investigators for the latest trial of #ProstateCancer #Immunotherapy. But it’s is very hard to argue against Dr Kim Chi’s points about the limitation of #Contact-2 (Cabo atezo vs NHT) in #mCRPC @asco #GU24 Hard to see this changing practice based on current data

Congrats to the investigators for the latest trial of #ProstateCancer #Immunotherapy.

But it’s is very hard to argue against Dr Kim Chi’s points about the limitation of #Contact-2 (Cabo atezo vs NHT) in #mCRPC @asco #GU24

Hard to see this changing practice based on current data
Ravi A Madan M.D. (@dr_ravimadan) 's Twitter Profile Photo

Thoughtful #ProstateCancer study evaluating sequencing of #PARPi & Abi #GU24 small study (n~20) w/ wide CI’s made smaller w/limited cross over Highlights path forward for a larger trials perhaps in a cooperative group to definitively answer this necessary❓of combo vs sequence

Thoughtful #ProstateCancer study evaluating sequencing of #PARPi &amp; Abi #GU24

small study (n~20) w/ wide CI’s made smaller w/limited cross over 

Highlights path forward for a larger trials perhaps in a cooperative group to definitively answer this necessary❓of combo vs sequence
Ravi A Madan M.D. (@dr_ravimadan) 's Twitter Profile Photo

These are the 2 key slides from the #Talapro2 presentation @asco #GU25 Where HR crosses 1.0 in pts w/no known HRR mutation status & Gd3 toxicity difference of 75% vs 45% I think there is still much to discussion to be had of value of #PARP +#ARPI in unselected #ProstateCancer

These are the 2 key slides from the #Talapro2 presentation @asco #GU25

Where HR crosses 1.0 in pts w/no known
HRR mutation status &amp; Gd3 toxicity difference of 75% vs 45% 

I think there is still much to discussion to be had of value of #PARP +#ARPI in unselected #ProstateCancer
Edwin Posadas, MD (@edwinposadasmd) 's Twitter Profile Photo

Proud of our #CedarsSinai #UCLA team for developing a new #liquidbiopsy based on EV subsets- we can make a custom #liquidbiopsy for almost any surface target! Check out our paper! sciencedirect.com/science/articl…

Ravi A Madan M.D. (@dr_ravimadan) 's Twitter Profile Photo

As new #mCSPC #PFS data is unveiled w/#PARP & Lu-PSMA it is worth nothing all previous mCSPC trials showed OS despite large functional cross overs Did we lower standard to PFS when both agents are approved for mCRPC? 🤔 #ProstateCancer #ASCO25 nature.com/articles/s4158…

Edwin Posadas, MD (@edwinposadasmd) 's Twitter Profile Photo

Great discussion from Angela Jia: contextualizing these 2 abstracts was key. Love the point of PSMA-PET and STAMPEDE when interpreting this data and contemporary RT approaches for localized PCA #ASCO25

Great discussion from Angela Jia: contextualizing these 2 abstracts was key.  Love the point of PSMA-PET and STAMPEDE when interpreting this data and contemporary RT approaches for localized PCA #ASCO25
Edwin Posadas, MD (@edwinposadasmd) 's Twitter Profile Photo

What did I learn at #ASCO2025 ? 1. Increasing intensity of treatment improves PFS& toxicity- still need OS data for shared decision making 2. Powerful new treatments for #ProstateCancer are coming. get patients on trial 3. Get biomarkers on your #ProstateCancer Thanks everyone!