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Older people who regularly do endurance exercise maintain similar muscle health to younger people The research suggests inactivity has a greater effect on some muscle characteristics than simply getting older Read more 🔽 kcl.ac.uk/news/muscle-he…

How do endurance exercise and the ageing process affect the positioning and number of myonuclei within muscle fibres? Edmund Battey (Physiology at KCL) et al. investigate in this article! 📜buff.ly/3UuaytN

After countless requests, we're thrilled to introduce PK Mito Orange FX - a fixable variant of PKMO. PKMO FX allows immunolabeling and CLEM approaches. Happy to have contributed to this project led by Zhixing Chen and Christian Jüngst. #mitochondria pnas.org/doi/10.1073/pn…

In this work, driven by amazing postdoc in our team Andrea Irazoki, we found that adaptations to cancer in mice critically depend on housing temperature. biorxiv.org/content/10.110…

Fully funded PhD opportunity with myself, Andrew Capel and Liam Heaney now available. Skeletal muscle sex differences | Postgraduate study | Loughborough University lboro.ac.uk/study/postgrad…

It's #FluorescenceFriday, and we love muscle fibers. So cool to visualize this plasma membrane-targeted biosensor in mature muscle fibers! It seems that the protein also allows us to see the T-tubule system (?) Ed Battey #FluorescenceFriday

New pre-print from the lab spearheaded by former visiting researcher in our group Ed Battey & supported by postdoc Dipsikha Biswas 🇵🇸🇺🇦🌻 Protocol for simultaneous visualization of different muscle compartments in cryosections of whole lower mouse hindlimbs. biorxiv.org/content/10.110…

#Cellsize is important for many cellular processes, including biosynthesis, organelle homeostasis and development. If you need an overview of how cell size is controlled, and how it affects cell function, we have you covered: doi.org/10.1152/physre… Yagya Chadha Arohi Khurana

New protocol paper from the lab for muscle fibre typing in whole lower mouse hindlimbs. Spearheaded by former visiting researcher in our group Ed Battey ,supported by postdoc Dipsikha Biswas 🇵🇸🇺🇦🌻 & in collaboration with Pascal Maire & Matthew Dos Santos. star-protocols.cell.com/protocols/3824

We have an exciting opening for a postdoc in our lab King's BHF Centre Hoping to appoint someone within the next few weeks. Link to advert here: my.corehr.com/pls/coreportal… Pls RT!

Metabolic myofiber typing on Cryosections of mouse whole hindlimb muscle MYH7/MYH2/MYH4 co-staining MYH1 DSHB Videos: How to use Cryotome MyoVision 2.0 MuscleJ2 Kei Sakamoto STAR Protocols 2024 star-protocols.cell.com/protocols/3824

In our latest study led by Tang Cam Phung Pham, we found that the mitochondrial (mt) protein SLIRP is a PGC-1α target that regulates mt structure, respiration, and mt-mRNA in muscle. And exercise restored these functions, even with SLIRP disruption and low mt-mRNA! nature.com/articles/s4146…

I've joined blue sky ☀️ bsky.app/profile/edbatt…

New pre-print from the lab NNF Center for Basic Metabolic Research (CBMR) spearheaded by PhD student Conchita & in collaboration with the Zeqiraj group University of Leeds ; providing structure-based molecular insights & cellular actions of the potent #AMPK inhibitor, BAY-3827 biorxiv.org/content/10.110…