1/ Approach to Ascites Thread

▪️3-step approach (PMN, SAAG, protein)
▪️Lab evaluation
▪️Differential by fluid color
▪️Correction for bloody fluid
▪️Ascites DDx square (SAAG x Protein)
▪️Bacterial peritonitis profiles
▪️Runyon’s criteria for secondary infection

#LiverTwitter 👊

1/

WHAT the heck is GGT?

#tweetorial #livertwitter #medtwitter

People with PSC have a unique pattern of bile acid synthesis

They sampled bile using ERCP among controls (no biliary disease), other cholestasis, and early PSC

And they discovered something important about psc pathophysiology

journals.lww.com/hepcomm/fullte…

In Hepatology Communications

1 de cada 4 pacientes con #cirrosis tienen dolor moderado/severo:

🇺🇸 n=5333
👀 Especialmente a nivel abdominal (44%)
💊 Uso frecuente de analgésicos (>50%), sobre todo opioides
🏥 El dolor significativo se asoció a un mayor uso de recursos sanitarios, como visitas a urgencias y

being a #chiefresident is truly the weirdest job in the world, but with just over one week left, I’ve been really reflecting on what a growth experience this has been both personally and professionally.

here are 12 things I learned (other than how to be a much better educator):

Every year outside my office I watch these geese raise their babies

Everybody talks about using the biomarker PEth to detect alcohol intake. But it's costly: $100-300.

Instead, start doing a good motivational interviewing with the patient following the RULE method. It takes time and empathy, but it's much cheaper.

#livertwitter #medX

Our latest work on #liver lipophagy and Rab5 is published in Hepatology Communications today! #alcohol AASLD
journals.lww.com/hepcomm/fullte…

Major findings in thread below:

Chronic pain in #cirrhosis is common and morbid - and we need to do something about it

The great Jessica Rubin in Hepatology Communications journals.lww.com/hepcomm/fullte…

All about PNPLA3 in Hepatology Communications today

1⃣PNPLA3 in #cirrhosis
⬆️Risk of HCC
↔️No diff in decompensation
journals.lww.com/hepcomm/fullte…

2⃣What do patients think about PNPLA3 testing?
Ground breaking qualitative work Jonathan G. Stine, MD MSc, FACP
journals.lww.com/hepcomm/fullte…

Excited to share our latest research in Hepatology Communications on the patient journey in #MASH !
Patient experiences, misdiagnoses, impact of genetic & ethnic factors and more!
🔑 findings highlight need for better clinician communication and support systems.

journals.lww.com/hepcomm/fullte…

Why two people that drink the same amount of alcohol, one develops cirrhosis and the other does not?

In the GenomALC Consortium, we found 20 genetic variants that influence susceptibility to cirrhosis.

t.ly/13NJ1 Hepatology Communications #livertwitter

Phenomenal talk by Patty Pringle Bloom, M.D. at #DDW2024 shark tank! 🦈

Naltrexone in AUD and liver disease:

🥇Should be 1st line

🔹Start: 50 mg daily, also available as monthly subcutaneous

🔹Use freely in Child’s A/B, ⚠️ in C but benefits will probably outweigh the theoretical risks as 🍸is ☠️for liver

#AGAGastroSquad AASLD Digestive Disease Week

Obligatory #DDW2024 sign pic with the fellows of UMichGIHep-Fellowship - all the learning, groundbreaking research and so much fun with the best people. 〽️💛💙 #goblue #AGAGastroSquad

Very nice episode from ⁦The Curbsiders⁩ with ⁦Arthur Kim⁩ on hepatitis B

Includes Shout out to ⁦Su Wang⁩
podcasts.apple.com/us/podcast/the…