Atrial fibrillation is the most common heart rhythm disorder, but there’s a lot we still don’t understand about the condition.

Findings from a CIHR-funded research team led by Dr. Robert Rose U Calgary could lead to new preventive treatments.

#HeartMonth
cumming.ucalgary.ca/news/ucalgary-…

Our new paper on natriuretic peptides and #AtrialFibrillation now available here:

Natriuretic Peptide Receptor B Protects Against Atrial Fibrillation by Controlling Atrial cAMP Via Phosphodiesterase 2 | Circulation: Arrhythmia and Electrophysiology ahajournals.org/doi/abs/10.116…

These authors won the #APSselect award in AJP-Heart and Circ for 'Chronic testosterone deficiency increases late inward sodium current & promotes triggered activity in ventricular myocytes from aging male mice'👏

ow.ly/Vblt50PJl2n

Manish Mishra Robert Rose, PhD, FHRS Susan Howlett

New study demonstrates protective effects of GLP-1 on atrial fibrillation in a mouse model of type 2 diabetes via ion channel and antifibrosis mechanisms. bit.ly/3P1nUK4

#AFib #EPeeps #diabetes #T2D #JACCBTS #CardioTwitter Robert Rose, PhD, FHRS

Once again, we're honored to be recipients of CPKC’s #CPKCHasHeart #ClearRounds4Heart program Spruce Meadows which will support our efforts to advance personalized & precise cardiovascular health therapies. Read more at ucalgary.ca/news/generosit…

UCalgaryMedicine @ucalgary…

September is Atrial Fibrillation Awareness month! #KnowYourRhythm #Epeeps #AtrialFibrillationAwareness EP_Bot American College of Cardiology Arun Sridhar Rachita Navara, MD FACC FHRS Jim Cheung Stavros Mountantonakis Nazem Akoum Kamala Tamirisa MD Mohit Turagam Ijeoma Ekeruo MD Rajesh Kabra Rakesh Gopinath

Our new publication on mechanisms of chronotropic incompetence and sinoatrial node dysfunction now available here:
Libin Cardiovascular Institute

PDE4D mediates impaired β-adrenergic receptor signaling in the sinoatrial node in mice with hypertensive heart disease academic.oup.com/cardiovascres/…

important information on personalized care for atrial fibrillation:

Investigating the link between aging & arrhythmias, Dr. Lockhart Jamieson, PhD, aims to determine innovative therapies to prevent serious arrhythmias in the elderly. Jamieson is one of 16 #UCalgary postdocs to receive CIHR Postdoctoral Fellowships this year. Read more ➡️…

Important Na channel review here:

Check out the last review about ryanodinopathies. Both gain of function and loss of function underlie fatal arrhythmia. CPVT and beyond.
'RYR2-ryanodinopathies: from calcium overload to calcium deficiency.'
Europace Editor-in-Chief

doi.org/10.1093/europa…

Great to collaborate with Susan Howlett and her team on this study:

Chronic Testosterone Deficiency Increases Late Inward Sodium Current and Promotes Triggered Activity in Ventricular Myocytes from Aging Male Mice journals.physiology.org/doi/abs/10.115…

Wang et al. discovered the novel role of #FKBP5 -deficiency in #HIF1a activation & its subsequent impact on the transcription of #NCX1 . Learn more about the mechanism of NCX upregulation in #Afib at ahajrnls.org/3r9ejZz
Jia Song Na Li (李娜) Lab @xwehrens Jordi Heijman

Very elegant and exciting study!

Jessica Wager has earned a prestigious NSERC Scholarship for her investigation of fat tissue expansion and cell formation. By unraveling this process, we can gain a deeper understanding of obesity and its impact on the body. Congratulations! Read more: news.ucalgary.ca/news/masters-s……

In this study, NT-proBNP and hsTnT were associated with MACE in patients with T2D at high risk of atherosclerotic events, and in individuals with high levels of both biomarkers, dapagliflozin was associated with reduced MACE event rates. ja.ma/3VParrR

Congratulations to Dr. Kimesh Chetty, this year’s recipient of the Peter Russell Award, awarded to a fellow who exemplifies Dr. Russell’s passion for patients and medicine. #LibinCelebrates

Congrats to Dr. Waseem Hijazi for receiving the LB Mitchell Fellow Research Award. We are so excited to see where your career takes you! #LibinCelebrates

Congrats to Dr. Jeff Shaw for receiving the preceptor of the year for the Cardiology Training Program, as chosen by trainees. Your commitment to training the next generation of cardiologists is exemplary! #LibinCelebrates