New Article now online: KCNE1 is an auxiliary subunit of two distinct ion channel superfamilies zpr.io/H4vZR

Researchers Northwestern used the #MaestroPro MEA system to study an #iPSC model of neonatal epileptic encephalopathy. The authors conclude that targeting dyshomeostatically altered ion currents might offer a therapeutic strategy: axionbiosystems.com/resources/publ… #StemCell #Epilepsy

Dyshomeostatic modulation of Ca2+-activated K+ channels in a human neuronal model of KCNQ2 encephalopathy | eLife elifesciences.org/articles/64434

Untangling Cellular Changes in Pediatric Epilepsy news.feinberg.northwestern.edu/2021/02/untang…

Mark your calendar 📅 for the Chicago Chapter - SfN meeting on April 8-9! Outstanding speakers to come!👇 We are accepting submissions for #neuroartwork to populate our upcoming conference website and CSfN home page! Do not hesitate to contact us! #ScienceTwitter #Chicago #neuroscience

Depolarizing GABAA current in the prefrontal cortex is linked with cognitive impairment in a mouse model relevant for schizophrenia | Science Advances advances.sciencemag.org/content/7/14/e…

doi.org/10.1016/j.stem… This is how we make lemonade!

"Homozygous might be hemizygous: CRISPR/Cas9 editing in iPSCs results in detrimental on-target defects that escape standard quality controls" Simkin D [..] Kiskinis E. Stem Cell Reports 2022-02-22. doi.org/10.1016/j.stem…

‘Channeling’ therapeutic discovery for epileptic encephalopathy through iPSC technologies - ScienceDirect sciencedirect.com/science/articl…

‘Channeling’ therapeutic discovery for epileptic encephalopathy through iPSC technologies, online now, review article from Evangelos Kiskinis and colleagues. Dina Simkin Northwestern Feinberg School of Medicine cell.com/trends/pharmac…

biologicalpsychiatryjournal.com/article/S0006-…

This is a really great study out of Peter #Penzeslab using iPSC-derived excitatory and inhibitory neurons to model schizophrenia. One of the first publications to implement the iGABA differentiation method (Yang et al. 2017). sciencedirect.com/science/articl…

Please help find a grad student in my former lab, call (312) 744-8266 with any info

Just submitted my first R01 research grant on exploring #HomeostaticPlasticity in #iPSC models of #DevelopmentalEpilepsy! #KCNQ2 #ionchannels!

Very proud to announce my work on the 16p11.2 duplication mouse model is now published!! It’s been a looong journey with this guy but so glad it’s finally out there. Click below to learn more about #16p11 #CNV #autism #schizophrenia #epilepsy 🧵1/7 nature.com/articles/s4146…

The 2023 KCNQ2 CURE SUMMIT will bring together an outstanding community of researchers, clinicians, and families to advance knowledge of KCNQ2 and related neurodevelopmental disorders. #KCNQ2 #KV7 #KCNQ2cure

synthego.com/podcast/dina-s…

thedailybeast.com/articles/2015/…

Dear ion channels aficionados - Here we are! The provisional program of #channelopathy2018 meeting is online - check channelopathy.blog/channelopathy-…