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There remains a steep drop off in survival during the first three months for a subset of MSI-H patients receiving immunotherapy. There remains a lane for chemo+IO in this setting. Waiting on you COMMIT trial #GI25

Sad to learn that the #PancreaticCancer research program (PCARP) will receive no funds in the current FY. 😢 I served as program review chair for 3y & we really tried to fund areas that are of pivotal importance to patients (like cancer cachexia research) but underfunded at NCI.

Ipi/Nivo now FDA Oncology approved based off #Checkmate8HW: Ph 3, dMMR/MSI-H mCRC, Ipi (1mg/kg) + Nivo (240mg) Q3W for 4 cycles and then Nivo alone vs Nivo: - mPFS NR for Ipi/Nivo vs 39·3 months - ORR: 71% vs 58% - Any grade AEs 81% from Ipi/Nivo vs 71% Nivo alone. #OncTwitter

"Why do I no longer enjoy my favorite food and activities?" - an important question from our patients with cancer and cachexia! Cancer is a disease of the whole body, including the brain. Kepecs Lab Marco Pignatelli Míriam Ferrer Gonzalez Cancer Grand Challenges Cold Spring Harbor Laboratory science.org/doi/10.1126/sc…

The American Cancer Society journals are proud to support healthcare professionals in transforming their approach to cancer #cachexia. Join this new Knowledge Hub and access invaluable resources for your decision making! Expert faculty include Richard Dunne, MD & more. cancercachexia.knowledgehub.wiley.com/?utm_source=or…

The American Cancer Society journals are proud to support healthcare professionals in transforming their approach to cancer #cachexia. Join this new Knowledge Hub and access invaluable resources for your decision making! Expert faculty include Richard Dunne, MD & more. cancercachexia.knowledgehub.wiley.com/?utm_source=or…

Congratulations to Gary Morrow ⁦Wilmot Cancer Institute⁩ on receiving the ⁦UR Medicine⁩ lifetime mentorship award. So well deserved!

#ASCO25 is just a few days away! At 📍Marriott Marquis, May 31, 6:30-9PM, lets discuss the current SoC & practice changing/reinforcing data! ✅ Register: bit.ly/aioasco25 #AdvInOnc25 #OncTwitter #bcsm #lcsm #gism #gusm #MedTwitter SignifyMD

📣 Big News! The Cancer Cachexia Society Society is launching the first-ever Cancer Cachexia Awareness Day! 🗓️ Starting this year, the 4th Friday of every September = Cancer Cachexia Awareness Day! #CancerCachexiaAwarenessDay2025

🚨 New in JCO: IL-6R blockade w/tocilizumab protects muscle in pts w/ #pancreaticcancer on gem/nab-paclitaxel, w/ no benefit for PFS, OS6mos. Precision cachexia therapy? Grateful for 9-yr collab w/Herlev team. #cancercachexia correlatives funded by National Cancer Institute ascopubs.org/doi/full/10.12…

Retifanlimab now U.S. FDA approved based off #POD1UM303: Ph III, recurrent or 1L metastatic squamous cell anal carcinoma, Carbo-Pac +/- Retifanlimab (anti-PD1): - ⬆️ mPFS: 9.3mos vs 7.4mos (HR 0.63) - ⬆️ mOS: 29.2mos vs 23mos (HR 0.70) - ORR 55.8% vs 44.2% #OncTwitter

Checkmate 577 data final OS analysis. Key Subgroups reported: HR of 0.92 for OS in patients with esophageal adenocarcinoma with adjuvant nivolumab and tumors that are PDL1+ driving small benefit #ASCO25

No OS benefit see. In LEAP-015 study combining chemo +IO + lenvatinib I. First line advanced gastric cancer #ASCO2025

Destiny-Gastric -04 provides definitive results on sequencing 2nd line therapy in advanced gastric cancer : T-Dxd SUPERIOR to Tax/Ram #asco25

🔥🚨OncoAlert Hot off the press. Just published NEJM in conjunction with presentation ASCO #ASCO25 Results of #Challenge trial of: Structured #Exercise after adjuvant chemotherapy for #ColonCancer: ✅⬆️Disease-free survival ✅⬆️Overall survival 👇🏻 nejm.org/doi/full/10.10…

👀 Adding #immunotherapy to chemo in resected dMMR stage III Colon Cancer is the game changer we have all been waiting for…but would it be as good with less toxicity with IO alone #ASCO25

Matterhorn shows statistically significant improvement in event free survival when adding Durva (immunotherapy) to standard chemo in Resectable Gastric and GEJ Cancer (HR 0.71) #Asco25

We no longer have any excuses. We owe it to all colon cancer survivors to recommend exercise!! It could save your life! #ASCO25 #crcsm #exercise

Upstate NY Cancer Symposium: June 21st (Buffalo, NY). Register at bit.ly/upstate2025 1 day CME to focus on the current SoC and updates from #ASCO25 in commonly treated solid and hematologic malignancies. Faculty: Roswell Park Wilmot Cancer Institute Andrea Apolo, M.D. Joshua Sabari, MD

Looking for a phenomenal educational forum, with impeccable vibes, &a lovely venue ? Join us for the upstate NY cancer symposium. In addition to talking about CRC I will be provide analysis RE: the best wing places !! Oncology Brothers Richard Dunne, MD Roswell Park Tim Brown, MD MSCE