A bioinformatics web tool that enables the user to visualize, search and explore protein-ligand structural patterns within the entire Protein Data Bank. GSP4PDB: a web tool to visualize, search and explore protein-ligand structural patterns 👇👇👇👇👇👇 bmcbioinformatics.biomedcentral.com/articles/10.11….

Small molecule modulation of protein polymerization - a Viewpoint from Eric Fischer and myself now published in Chemical Society Reviews pubs.rsc.org/en/content/art…

Please RT: For those living in Paris, or willing to come and visit Paris for 1-2 days, here is an important announcement. Rob Phillips will give a series of 4 lectures at the Collège de France on Mondays 9, 16, 23 and 30 May. It's free, no registration needed. Just come and enjoy

Beyond amyloid: Immune, cerebrovascular, and metabolic contributions to Alzheimer disease in people with Down syndrome: cell.com/neuron/fulltex…

I’ve collected several (currently 13) of the Jupyter notebooks I put together for teaching Cheminformatics in a Git repo and made them runnable on Google Colab. Hopefully, others will find the notebooks useful for teaching or self-study. github.com/PatWalters/pra…

Here is the link to Rob Phillips' 1st lecture Collège de France college-de-france.fr/site/thomas-le… It introduces a view of quantitative biology, culminating in a definition of understanding that can answer the question of what sets the scale of sizes, time scales, concentrations, rates, energies etc

In Jan 2021, while having treatment for cervical cancer, I started filming myself. It started as a way to make sense of what was happening to me, but I soon realised there was a much bigger story, about how we approach cancer treatment in this country… telegraph.co.uk/health-fitness…

Really cool story 🔥- the cytoplasm is not “well-mixed” but represents a highly heterogeneous environment. ... demonstrates viscosity variation is independent of the cytoskeleton, cell cycle stage, and temperature – but increases under hyperosmotic shock.

Our work describing the modulation of co-translational protein folding by rational design and ribosome engineering was published by Nature Communications nature.com/articles/s4146… That was a long journey! Thank you! Minkoo Ahn Alkistis Mitropoulou and JC group:) UCL Biosciences

With the Picotti Lab we are hiring for a developer to set up a resource for protein dynamical information derived from proteomics data. Experience in web development and bioinformatics would be ideal. Long term perspective job with training opportunities jobs.ethz.ch/job/view/JOPG_…

If you are doing proteomics combined with protein structure/prediction analysis please check out the vignette of our R package protti! Any feedback and suggestions are very welcome!

Join the next free Aggregate webinar. Develop your understanding of the fundamental process of protein folding and its roles in human diseases. 🔗: ow.ly/4m9m50LuHHh Our expert speakers: Prof Danny Hatters, Picotti Lab, Xin Zhang, Vendruscolo Lab, Ben Zhong TANG

It's been a tough week out there for layoffs- On the brighter side, there are many newcos excited to grow and hire. Let me know if you're interested in joining a brand new biotech start up in the Bay Area with founders Micha Rapé, Aaron Gitler, and more. lyterian.com

Why does Alzheimer's disease sweep through the brain in such a determined manner? Why do amyloid aggregates form in certain brain regions and not others? Why are some brain regions devastated and others spared? Join our team & help us find out! jobso.id/fh3q 🙏RT

I would say this is perhaps the most important paper in the amyloid field in the last 7 years. At least to me... nature.com/articles/s4158…

Molecular and environmental determinants of biomolecular condensate formation dlvr.it/SdM3GN

So, what’s new in our LiP-MS protocol for in situ #structural #proteomics? - The new analysis package, MSStatsLiP, developed with Olga Vitek 's group - Improved robustness and throughput - Lots of experimental design tips! rdcu.be/c2aGS #TeamMassSpec Nature Protocols

Excited to share updated preprint by Mangyu Choe showing that, contrary to textbook view, the role of allosteric regulation of glycolysis is not to control rate but to maintain ATP levels by preventing a futile cycle between upper and lower glycolysis. 🧵biorxiv.org/content/10.110…