A tweetorial explainer on Puente-Lelievre et al (2023). We are very excited about this paper & its implications for phylogenetics. Here's why! (Work stems from HFSP grant "How life got moving: reconstructing and re-evolving the bacterial flagellar motor" x.com/SBSatEd/status…)

Maximum likelihood structural phylogeny beyond the twilight zone by combining Foldseek's 3Di alphabet with AA alignments. ML trees resolve the topology of distantly related proteins where traditional AA methods fall short. 📄biorxiv.org/content/10.110… 💾github.com/nmatzke/3diphy

On use of tertiary structure characters in hidden Markov models for protein fold prediction biorxiv.org/cgi/content/sh… #biorxiv_bioinfo

What has just put together 1) #protein #structures 2) hidden #Markov models 3) protein fold #prediction in the era of large scale structure generation using #Alphafold & #ESMFold ? #Science #MachineLearning #Bioinformatics #ESMAtlas

Latest work from the lab :: "Deep-PK: deep learning for small molecule pharmacokinetic and toxicity prediction," has been published in Nucleic Acids Research. #deeplearning #MachineLearning #AcademicTwitter academic.oup.com/nar/advance-ar…

🚀 Excited to share our latest research! 🚀 1/ 🧬 Just published: "DDMut-PPI: predicting effects of mutations on protein–protein interactions using graph-based deep learning" 📄🔗doi.org/10.1093/nar/gk… 🌐biosig.lab.uq.edu.au/ddmut_ppi

Stephanie Portelli (from the David Ascher lab) and ML can sleuth through genes better than any detective. Her positive results highlight the role #ML can play in interpreting #Genomic variants. #Science #AcademicChatter

Presented my work today at the ABACBS Seminar Series - thanks all for the feedback and opportunity! David Ascher #ML #Genomics #AcademicChatter

Thrilled to be able to finally announce the Queensland Emory Vaccine Centre #QEVC, a partnership between ⁦UQ News⁩ and ⁦Emory University⁩ A new state-of-the-art 1200m2 facility providing the expertise and infrastructure for vaccine innovation. stories.uq.edu.au/news/2024/uq-s…

Deeply honoured to be part of a wonderful team recognised by this award: Biosulfur Recyclers - 2024 Chemistry Biology Interface Horizon Prize: Rita and John Cornforth Award winner rsc.org/prizes-funding… via Royal Society of Chemistry

A massive congratulations to the team at Biosulfur Recyclers - including UQ Chemistry and Molecular Biosciences's David Ascher and his team - for winning a Royal Society of Chemistry Horizon Prize! 🥳🎉 Read more about the project: tinyurl.com/26aez7bc UQ News #RSCPrizes

Great talk by David Ascher (UQ) providing an overview of his work using AI and structural biology impacting across many biomedical problems #AIxBIO Centre for Computational Biomedical Sciences John Curtin School of Medical Research, ANU

AI×BIO 2024,the Inaugural ANU Symposium in Computational Biology, Biomedicine, and AI, jointly organised by ANU School of Computing is currently underway at #JCSMR. Uniting AI, biology, and biomedicine to revolutionise health outcomes and knowledge discovery. #AIxBIO2024

The biotech program team

What a fantastic team! The postgraduate biotechnology program at UQ News UQ Chemistry and Molecular Biosciences is world leading and with the local expansion in biotech R&D and industry engagement, presents an ideal opportunity to expand the student experience. #UQBiotech

AlzDiscovery: A computational tool to identify Alzheimer's disease-causing missense mutations using protein structure information 1/ 🧬 Machine learning meets Alzheimer’s disease research! AlzDiscovery is a new computational tool that helps predict Alzheimer’s disease-causing

🚀 We’re wrapping up our seminar series for the year on a high note! ✨Next Monday, David Ascher from UQ News will be our Judith and David Coffey speaker. ⏱️October 14, 1pm (AEST) 👉bit.ly/3DPCCP3

Proud to see this paper from the lab out today nature showing how rifaximin use is driving dapto-R in VRE. Many years of work, great multi-disciplinary collaborations. Led by Adrianna Turner and Glen Carter Doherty Institute UniMelb MDHS Austin Health rdcu.be/dXUDt

Also proud to share my PhD work out today in nature rdcu.be/dXUDt Thankful for great supervisors and many collaborators who made this work possible

Want to explore new frontiers in computational biology? We are applying AI, quantum computing, population genomics and more across clinical and industrial applications. Come join a dynamic group at Baker Institute and UQ Science: seek.com.au/job/79827007?t…