🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

COLOSSUS partners RCSI, Vall d’Hebron Institute of Oncology (VHIO), Università di Torino, @vib_mec_core, University College Dublin Uni Heidelberg: Molecular Subtyping Combined with Biological Pathway Analyses to Study Regorafenib Response in Clinically Relevant Mouse Models of Colorectal Cancer" colossusproject.eu/news/colossus-…

Incredibly excited to share our paper ‘Somatic mutation rates scale with lifespan across mammals’ now published @nature. nature.com/articles/s4158… An illustrated & updated tweetorial… [1/24]

Our work on image-based profiling of patient-derived organoids is in print! - thank you to all co-authors and mentors - Johannes Betge, @bengrauscher, Jan Sauer, @prof_ebert & Michael Boutros nature.com/articles/s4146…

Our paper on drug-induced phenotypes in colorectal cancer #organoids is now online Nature Communications. Thanks to all involved, especially Niklas Rindtorff Boutroslab @prof_ebert @bengrauscher nature.com/articles/s4146…

Recently published #CancerResearch: Image-based #smallmolecule profiling study in patient derived #cancer #organoids by Johannes Betge Michael Boutros @niklas_TR @prof_ebert et al. @dkfz Cancer at Nature Portfolio go.nature.com/39AaOTs

Congratulations Michael Boutros, well deserved and a great choice for Nationale Akademie der Wissenschaften Leopoldina

Anti-cancer fluoropyrimidine drugs have antibacterial effects on the gut microbiome, and these drugs can be metabolized by gut bacteria via conserved pathways also found in mammalian hosts, according to a Nature Microbiology paper. go.nature.com/3UxiuZb

Interested in using organoids to study #ColorectalCancer? 🤔 This International Journal of Cancer #review from Drs. Rene Jackstadt and Johannes Betge (Johannes Betge) at DKFZ discusses developments in organoid-based research, with a focus on those in colorectal cancer. 🔗: bit.ly/3rifym0

🔥NOW ONLINE 🔝 Read the thorough review by Johannes Betge and Jackstadt_lab on #organoid –based research for #colorectalcancer 🔓OPEN ACCESS ➡️doi.org/10.1002/ijc.34…

Glad to announce I will be joining the Department of Medicine II in Mannheim as a junior group leader in January 2023! This is finally a dream come true, the child in me who wished to be a scientist feels very satisfied. I am extremely grateful to all my previous mentors.

Workshop on novel approaches to drug #Wnt signaling pathways in human diseases - March 17th, 2023 in #Heidelberg with presentations from academia and industry. Organized by @sfb1324 DFG public | @[email protected] Uni Heidelberg @dkfz EMBL Health + Life Science Alliance Heidelberg Mannheim sfb1324.de/event/wnt-work… Please RT

Wnt proteins are key regulators of many developmental and disease processes. Recent studies have shed light on how they are secreted, and how this process is regulated. Read our review on Wnt protein secretion. #Wnt #Communication #cancer @sfb1324 journals.biologists.com/dev/article/15…

Excited to host the first #organoids in #cancer #summerschool DKFZ Universitätsmedizin Uni Heidelberg NCT Heidelberg HI-STEM - Cancer and Stem Cells in Heidelberg with Jackstadt_lab, Johannes Betge and Köhler Lab. Keynotes from Dream3D Lab; Florian Greten and Xiling Shen! Details and registration at indico.dkfz.de/event/729/.

Looking forward to 2 days packed with cutting-edge science during the first #organoids in #cancer #summerschool DKFZ Universitätsmedizin Uni Heidelberg NCT Heidelberg HI-STEM - Cancer and Stem Cells in Heidelberg; made possible by generous support from Health + Life Science Alliance Heidelberg Mannheim!

Wishing all of you wonderful people here a very merry GI Christmas 😅🎄

We are searching for a motivated postdoc: Are you interested in unravelling how niche signals and tumour microenvironment impact genome stability in the intestine? Check out and apply to project #2 health-life-sciences.de/jobs/postdocap… Deadline: 5th April. Contacts: Sergio Perez Acebron SotilloLab

youtube.com/watch?v=ukT9Jm… Schöner Film über unsere Klinik in Mannheim und das Team der Station 1-42a! Universitätsmedizin Mannheim @prof_ebert Uni Heidelberg

Together with Jovan Tanevski and Johannes Betge, we are looking for a computational postdoc interested in the combination of modeling tissue organization patterns from spatial proteomics data in a highly clinically relevant cancer context. Funding available: health-life-sciences.de/opportunities/…