Wild to be living in a time where we’re building artificial brains and engineering human ones.

Claude 4.5 really doesn’t like discussing biology. Even the most innocuous prompts can trigger a safety flag.

Very happy to share our multi-lab preprint: Degeneration and Impaired Resilience of Skull Bone & Hematopoietic Bone Marrow 👇 biorxiv.org/cgi/content/sh… The skull shows pronounced age-related decline, while vertebrae are relatively spared 🧵

The first time I ever saw a protein structure was when I joined the Folding@home team for the AppleInsider message board 20+ years ago. A collective realization that communities + technology could be used for good. Don’t underestimate the impact of a culty fanbase that’s

Arc is hiring a unique role to lead the Virtual Cell Challenge. In its first year the Challenge has already attracted participation from thousands of top bio AI researchers and support from sponsors like NVIDIA. We need someone to help us make this annual competition historically

So cool to see Dave deBronkart on the author list!! So necessary to have auditability in health AI and patient care. Mighty #HeathenSlut Casey🇺🇦🌟 would have loved this too.

My fiancé sent me this screenshot of a conversation he had with Claude last night.

Had to do a double take because I thought this was my dog and wondered what he’s studying.

Holy shit...Google just built an AI that learns from its own mistakes in real time. New paper dropped on ReasoningBank. The idea is pretty simple but nobody's done it this way before. Instead of just saving chat history or raw logs, it pulls out the actual reasoning patterns,

2025 pharma M&A surges to $70 billion in major deals. $AKRO $VRNA $SWTX $BPMC $ETNB $ITCI $MTSR and more gone. $PTGX next? drugdiscoverytrends.com/2025-pharma-ma…

Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy nature doi.org/10.1038/s41586… 👉PNI & CINI of tumour-associated nerves are associated with poor response to anti-PD-1 👉CINI-driven anti-PD-1 resistance can be reversed ESMO - Eur. Oncology

David Pfau This is such a mathematician move. I love this.

Proximity induction + de novo protein design 😍

Shohei 💙 #NLCS

This is what I keep coming back to

What? This is huge for in vitro directed evolution

Would love to see a bio/AI focused role like this, know some excellent people graduating soon that would be perfect.

Congratulations to ARPA-H for recruiting Alicia Jackson as ARPA-H director!

Seeing CADASIL and connective tissue disorders on this list isn’t surprising. Genetic screening is low hanging fruit for improving clinical trial design and interpretation.