The renaissance in #EBM and #GRADE continues: the third article in the #BMJ series presenting Core GRADE, the essentials of the GRADE approach to certainty of evidence and strength of recommendations. Today Core GRADE’s approach to addressing #inconsistency in results.

This classic #GRADE paper from the era before GRADE got too complicated shows you how to create #SummaryofFindings tables for continuous outcomes and in particular patient-reported outcomes. #EBM #PRO #Medicine pubmed.ncbi.nlm.nih.gov/23116689/

Honored and privileged to be part of this collaborative work on MRONJ and Dental Implants in patients with Osteoporosis!! AACE #EndocrinePractice #MedTwitter Article 🔗 kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F%2…

Before this classic #GRADE paper we thought we were rating certainty in the point estimate. In this 2017 #JCE paper, we announced our revelation: we are rating our certainty that the truth lies on one side of a threshold or in particular range. #EBM #Medicine

A series of 7 papers, Core #GRADE, the essentials of GRADE providing all you need to rate #CertaintyofEvidence and move from evidence to recommendations, is currently appearing in the #BMJ. Today, dealing with #RiskofBias, publication bias, and large effects. #EBM #medicine #CPG

As previous post, an 2-minute video in which I describe the fourth of 7 Core #GRADE articles appearing in the #BMJ. This one, published today, shows address #RiskofBias in #SystematicReviews and #Guidelines. #EBM #Medicine #RoB #SR Publication link: bmj.com/content/389/bm…

Evaluating bone turnover, mineralization, and volume of patients with chronic kidney disease can guide the approach to preventing fractures. Read more in #EndocrinePractice: endocrinepractice.org/article/S1530-… Vin Tangpricha, MD, PhD @Els_ENDO #endocrinology

Excellent review article by Dr Rob Wermers of Mayo Clinic Endocrinology

Honoured to present today at AACE alongside my mentor Prof. Aliya Khan and Dr. Jan de Beur on the new international guidelines for X-linked Hypophosphatemia! A fantastic program at #AACE2025. aace2025.d365.events/directory/sess…

Core #GRADE guidance today in the #BMJ addresses the essentials of evaluating #indirectness with respect to patients (old vs young), interventions (fully versus partially adherent), comparators (#placebo vs active) and outcomes (surrogate vs patient-important).

In this 2 minute video I summarize Core #GRADE guidance from today’s 5th article in our series in the #BMJ presenting the essentials of using GRADE – this one addressing #indirectEvidence (limitations in applicability or generalizability to the target #PICO at hand). Publication:

Today in #BMJ, 6th in 7 part series on the essentials of #GRADE – Core GRADE: creating excellent Summary of Findings tables allowing clinicians and guideline developers to easily and comprehensively grasp evidence that will assist patients to make optimal decisions.

In a 2 minute video I summarize Core #GRADE guidance from today’s 6th article in our #BMJ series of the essentials of using GRADE – this one addressing how to create optimal Summary of Finding tables that facilitate optimal #guidelines and shared decision making.

Paper just published in #BMJ_EBM paper provides additional details to one of the more challenging aspects of Core #GRADE: how to deal with the situation when certainty rating threshold is the null and point estimate near the threshold. pubmed.ncbi.nlm.nih.gov/40044276/

This finding from the Osteonecrosis of the Jaw Taskforce supports the safe placement of implants without discontinuation of antiresorptive therapy used for osteoporosis management: endocrinepractice.org/article/S1530-… #endocrinology #diabetes Elsevier Endocrinology & Diabetes Vin Tangpricha, MD, PhD

You are trying to help someone who is ambivalent between mutually exclusive actions A and B. You think A clearly preferable and say so. This is the best way to drive them toward B. To help: listen, empathize and help clarify relative merits. They will then find their way.

This finding from the Osteonecrosis of the Jaw Taskforce supports the safe placement of implants without discontinuation of antiresorptive therapy used for osteoporosis management: endocrinepractice.org/article/S1530-… #endocrinology #diabetes @Els_ENDO Vin Tangpricha, MD, PhD

Association of gestational #thyroid function and thyroid #autoimmunity with #gestational #diabetes: a systematic review and individual participant meta-analysis thelancet.com/journals/landi… #ENDO2025

Multiple endocrine neoplasia type 1 (#MEN1): recommendations and guidelines for best practice thelancet.com/journals/landi… #FREE to read with registration (also FREE) #ENDO2025

Treatments for #MEN1-associated endocrine tumours: three systematic reviews and a meta-analysis thelancet.com/journals/landi… #OpenAccess