Can neurons drop in and out of memory engrams even though training-activated neurons remain necessary and sufficient for recall? We found that memory engrams are dynamic with engram cell turnover being linked to the emergence of memory selectivity. biorxiv.org/cgi/content/sh…

Excited to share our Nature Communications paper that aimed to identify memory engrams distributed throughout the brain. 7 years in the making. This one needed a lot of help from so many fantastic authors! rdcu.be/cKDwn

Can we please stop framing mask wearing as something that some of us "DESIRE" to wear on our campuses? This diminishes the very real risk of transmission to children who cannot be vaccinated and to individuals who are immunocompromised or otherwise at high risk. 1/

Metabolically driven action potentials serve neuronal energy homeostasis and protect from reactive oxygen species biorxiv.org/cgi/content/sh… #biorxiv_neursci

Dear #neurotwitter, we dropped this onto bioRxiv Neuroscience for your perusal. It's an unusual piece from my lab & I really, really enjoyed working on it with @chc1987. Here it is: Metabolically spikes serve neuronal energy homeostasis (and protect neurons). doi.org/10.1101/2022.1…

A recent preprint from the Rajasethupathy lab found a thalamo-cortical circuit critical for systems consolidation that supports key predictions of our previous computational model with Douglas Feitosa Tomé and Sadra Sadeh! Computational model: nature.com/articles/s4146…

Next Thursday World Wide Neuro 🧠🗺️! With dr. ashley juavinett, Matt Kelley, Patrick Mineault Join us here: world-wide.org/Neuro/WWNeuRise

Our new study on the temporal evolution of memory engrams is out in Nature Neuroscience! Check out the full paper with Douglas Feitosa Tomé, Ying Zhang, Tomomi Aida, Olivia Mosto, Yifeng Lu, Mandy Chen, Sadra Sadeh, Dheeraj Roy and ClopathLab! nature.com/articles/s4159…

How might complex representations in hippocampus emerge alongside complex behavior? How can we model the learning of "split" state representations?  Check out the latest work of Ian Cone and ClopathLab, just published in Nature Communications: doi.org/10.1038/s41467…

#Memory engrams are dynamic, and changes in engram composition mediated by inhibitory plasticity are crucial for the emergence of memory selectivity Douglas Feitosa Tomé Dheeraj Roy ClopathLab nature.com/articles/s4159…

The Clopath Lab is 🔥hiring 🔥a PostDoc and a fully-funded PhD student in the field of computational neuroscience 🧠 at Imperial College London. Details for application here cclopath.bg-research.cc.ic.ac.uk

1/ Today in Science, we train a neural net from scratch through the eyes and ears of one child. The model learns to map words to visual referents, showing how grounded language learning from just one child's perspective is possible with today's AI tools. science.org/doi/10.1126/sc…

This gets me every time: ChatGPT's explanation of scientific and mathematical concepts in the style of various poetry and song. Here is Einstein's general relativity in the style of Shakespeare. When will we have a theory of this type of generation and what might it look like?

Excited about our long-brewing paper exploring dynamics in multi-regional neural circuits in a delayed movement task. Driven by@esthersselva, Yi Liu, and including Jennifer Colonell, Nuo Li and Shaul Druckmann and others (the MAP collaboration): cell.com/cell/fulltext/… (1/7)

RatInABox🐀📦- which began accidentally from some old code I had lying around - grew to become a massive toolkit for navigational research. It's immensely gratifying to see it finally published and being used in such a variety of ways across the field. elifesciences.org/articles/85274

Come check out our poster at COSYNE 2024 today at 12:30 pm! - via #Whova Event Platform tinyurl.com/29phmtaw #cosyne2024 #cosyne24

1/6 Surrogate gradients (SGs) are empirically successful at training spiking neural networks (SNNs). But why do they work so well, and what is their theoretical basis? In our new preprint led by Julia Gygax, we provide the answers: arxiv.org/abs/2404.14964

Come check out my poster at COSYNE 2025 later tonight: [1-012] Parallel memory generalization and discrimination across brain regions. Looking forward to engaging discussions! #cosyne2025 #cosyne25 - via #Whova event app

Glad to have joined #EngramsandEnsembles2025 in #Dublin! Not only did I attend great talks and posters on everything #learning and #memory, but I also hung out with many fun fellow scientists!