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Our work led by Valeria Añorve-Garibay with Diego Ortega-Del Vecchyo and Emilia Huerta on ways in which natural selection acting on complex traits hampers the predictive accuracy of polygenic scores in ancient samples is now on bioRxiv! biorxiv.org/content/10.110…

Our preprint looking at the impact of stabilizing and directional selection on the prediction of complex traits in ancient samples is out. This work was spearheaded by Valeria Añorve-Garibay in collaboration with Mashaal Sohail and Emilia Huerta .

New paper out in PLOS Biology! Two SNPs fully explain kākāpō color polymorphism, likely under balancing selection from extinct predators🦜🦅🧬 Great collab of many evol biologists, conservation scientists and physicists, led by the brilliant Lara Urban journals.plos.org/plosbiology/ar…

Excited to share our newest preprint - biorxiv.org/content/10.110… Based on the classic complementation studies of mutations, we propose a gene-based fitness model where two deleterious mutations on the same haplotype are more harmful than if they were on separate haplotypes.

✨️ I’m excited to share my second-author paper encapsulating most of my PhD work, which is out today in Science Magazine 🥰❤️. A new long non-coding RNA (lncRNA) underlying sex chromosome dosage compensation in the lizard Anolis 🦎 #MAYEX! 🧵👇 science.org/doi/10.1126/sc…

I am really happy to see the #preprint of our work studying #acral #melanoma tumours from 🇲🇽 Mexican patients out today! This has been a ~8 year-long work involving many colleagues from Mexico and abroad. Some of our findings here below.... ⬇️ (1/12)

I have received tenure! I got here thanks to the support from my students, colleagues, mentors and home institution ( LIIGH ). I plan to continue doing research on Theoretical Population Genetics and developing methods to understand how Evolution has shaped our past.

Será un honor participar en este evento en donde varios colegas de la UNAM expondremos sobre nuestras investigaciones en el campo de la genómica.

Interested in sedaDNA, aDNA, or forensic genetics? Join me in Copenhagen! I'm hiring a PhD and a Postdoc to start in 2025. Application deadline 28 November employment.ku.dk/phd/?show=1626… employment.ku.dk/all-vacancies/…

This is our genomic portray of a novel, diverse, and highly introgressed population of S. cerevisiae from the Neotropics. With 200+ new genomes of yeasts from open agave fermentations in 🇲🇽 and as part of the #YeastGenomesMx consortium efforts biorxiv.org/content/10.110… 🧵🧵🧵

Super excited to share the publication of our article on the First Year Results and Insights from the Mexican Rare Disease Patient Registry today in Rare!!! We launched this online self-registry for patients in Mexico to address the need for a national registry but also...(1/🧵)

We are thrilled to host Christian D. Huber Penn State today LIIGH! We are listening about mechanisms of admixture in human populations - and how we can infer them through #genetics!

Excited to share our review article on Denisovans, now out in Nature Genetics🥳I am very grateful to Emilia Huerta for making this possible! Check it out 🔎🧬 nature.com/articles/s4158…

I am truly honored to have been nominated to run for a Director position of Genetics Society of America! GSA members, vote before December 6. My candidacy statement can be found here: genetics-gsa.org/2024-election-…

For folks still here, the first big project from my group is pre-printed. Super talented postdoc Maria Akopyan explored how reference bias can skew estimates of diversity, demography, divergence and recombination rate with help from Ellie Armstrong 🦁🐯🐻 and @GMenchev. Thread 👇🏽

Don't forget to submit your abstract for ProbGen25. Deadline: January 10th, 2025. meetings.cshl.edu/meetings.aspx?…

Really happy this one is finally out! Tessa worked super hard to get it across the finish line. Please read if you are thinking about how to or if you should scale your sims.

📣New from Añorve-Garibay et al! 📄Natural selection acting on complex traits hampers the predictive accuracy of polygenic scores in ancient samples cell.com/ajhg/abstract/…

Our work is out in AJHG "Natural selection acting on complex traits hampers the predictive accuracy of polygenic scores in ancient samples." Great collaboration with Diego Ortega-Del Vecchyo & Emilia Huerta, led by talented LCG UNAM Juriquilla (LCGEJ) undergrad Valeria Añorve-Garibay, now a PhD student at CCMB at Brown.

Our paper is out! Happy to have collaborated with Mashaal Sohail , Emilia Huerta and Valeria Añorve-Garibay on this project. Here we analyzed how stabilizing and directional selection cause problems to predict traits in ancient samples.