How constrained is each gene in the human genome? Our work on estimating gene constraint using loss-of-function mutations along with gene features (expression patterns across tissues, protein language model embeddings, etc...) is now officially out! 🧵/8 nature.com/articles/s4158…

Talks from Valeria Añorve-Garibay and Eucharist Kun at #SMBE2024. Fun collaborations with Diego Ortega-Del Vecchyo Emilia Huerta and Vagheesh Narasimhan using ancient DNA, MXB, comparative genomics resources and multitudes of GWAS to ask questions about complex trait and disease evolution

Not just Ne (or Ne SMBE), Ne-more!!! Grateful to have been given the opportunity to organize a symposia on recent advancements in SMC’ methods with the best desk-mate in the entire world (aka elsie) and to present my recent work on Denisovan adaptive introgression!

What a lovely week attending #SMBE2024, with great scientists, talks, and posters. This is my first time with many of my colleagues in the same meeting ❤️. Thanks to the LOC for bringing SMBE to 🇲🇽

Last week, Rori shared her and Emilia's experience creating Science Wise at the IDEA (Inclusion, Diversity, Equity and Access) Symposium at SMBE! 🌟 #womeninSTEM #womeninscience

#SMBE2024 was a blast! Thanks to the local organizing committee and to OfficialSMBE for making it possible. We need more of these meetings in the global South to make our meetings more inclusive and diverse (1/5)

Oye, Conahcyt México, sugiero que retires de la evaluación de las estancias postdoctorales la pregunta 2 de la 2da. sección, que ahora lee "El plan de trabajo es adecuado y viable para ejecutarse y concluirse correctamente durante el periodo de vigencia de la estancia" (1/2)

¿Buscas a un perrito lleno de amor y energía? Aquí es 👇🏽

Un poquito retrasada, pero quiero compartirles con mucho orgullo que el pasado junio se titularon Athena Tamayo y Sometimes, A Serious Scientist de la LCG UNAM, ¡felicidades, Lic. Athena Tamayo y Lic. Emiliano Sánchez! 🎉Ambos proyectos en el laboratorio contribuyen a expandir las capacidades de CoRa.

Here is a video of my talk for those interested: youtube.com/watch?v=GmcUzg…

¡Felicitamos a nuestra investigadora, la Dra. Marcela Sandoval Marcela Sandoval-Velasco, por haber obtenido el Reconocimiento al Mérito Estatal en Investigación 2024! Este reconocimiento es entregado por parte del Consejo de Ciencia y Tecnología del Estado de Morelos. ¡Enhorabuena!

¿Me ayudan a compartir? 🐶🩵 #AdoptaNoCompres

Ahhhh salí en la portada (aunque nomás la foto jaja) lalupa.mx/2024/08/11/lic…

En honor a la cultura científica en nuestra bella Latam (x.com/mex_evo/status… ) MAÑANA en nuestro Miércoles de seminario contaremos con la participación de divulgadors de México🇲🇽, Chile🇨🇱 y Argentina🇦🇷, quienes compartirán su experiencia en la comunicación de la ciencia 👇🏾

Really a pleasure for me to introduce the last speaker of our session, Patricia Basurto! Paty is a senior PhD student in our group LIIGH 🇲🇽 and she is telling us about her project studying the #genetics and #genomics of #acral #melanoma in Mexican patients PASPCR

Our work led by Valeria Añorve-Garibay with Diego Ortega-Del Vecchyo and Emilia Huerta on ways in which natural selection acting on complex traits hampers the predictive accuracy of polygenic scores in ancient samples is now on bioRxiv! biorxiv.org/content/10.110…

Our preprint looking at the impact of stabilizing and directional selection on the prediction of complex traits in ancient samples is out. This work was spearheaded by Valeria Añorve-Garibay in collaboration with Mashaal Sohail and Emilia Huerta .

New paper out in PLOS Biology! Two SNPs fully explain kākāpō color polymorphism, likely under balancing selection from extinct predators🦜🦅🧬 Great collab of many evol biologists, conservation scientists and physicists, led by the brilliant Lara Urban journals.plos.org/plosbiology/ar…

Excited to share our newest preprint - biorxiv.org/content/10.110… Based on the classic complementation studies of mutations, we propose a gene-based fitness model where two deleterious mutations on the same haplotype are more harmful than if they were on separate haplotypes.

✨️ I’m excited to share my second-author paper encapsulating most of my PhD work, which is out today in Science Magazine 🥰❤️. A new long non-coding RNA (lncRNA) underlying sex chromosome dosage compensation in the lizard Anolis 🦎 #MAYEX! 🧵👇 science.org/doi/10.1126/sc…