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Our October issue is live! 🥳 nature.com/nmeth/volumes/… On the cover, single-cell DNA-RNA sequencing (SDR-seq) links genetic variants to gene expression. Artwork by Tobias Wuestefeld. Paper here: nature.com/articles/s4159…

The accepted dogma for dietary lipids was their absorption by the gut lining into our bloodstream. It turns out there's another way in, via our immune cells, influenced by the gut microbiome (as shown in mice) Science Magazine science.org/doi/10.1126/sc… science.org/doi/10.1126/sc…

HEBP2-governed glutamine competition between tumor and macrophages dictates immunotherapy efficacy in triple-negative breast cancer dlvr.it/TNcTW4

The secret to the naked mole-rats’ extraordinarily long life may lie in subtle changes to just four amino acids, researchers report in Science. scim.ag/46SVkot

Congrats again to all the awardees including our amazing Joshua C. Doloff member Jessica Stelzel, Mao lab member and collaborator (& former TA) Yining Zhu, and Denis Wirtz lab member (and newest collaborator) André Forjaz! You are all heavy hitters and rock stars! 🌟

We posted this preprint to bioRxiv Immunology that focuses on the idea that CD8 T cells can naturally survey and eliminate stem-cells in the colon epithelium that have neoantigens that are created by somatic mutation. This work was spearheaded by Jess Buck in the lab!

Check out our newest student spotlight on 2026 Siebel Scholar, Yining Zhu, and learn more about his research on how to better design lipid nanoparticles, that can carry genetic instructions (like mRNA) into the body to help treat diseases such as cancer. inbt.jhu.edu/siebel-scholar…

A surprise bonus from COVID-19 vaccines: bolstering cancer treatment | Science | AAAS science.org/content/articl…

Come work with us! We are looking for a Sr. Administrative Manager and you can learn more about the role here: jobs.jhu.edu/job/Baltimore-…

Mesenchymal thymic niche cells enable regeneration of the adult thymus and T cell immunity go.nature.com/3Jp6B72

Nature research paper: Multi-omic profiling reveals age-related immune dynamics in healthy adults go.nature.com/4nvIfq8

We have written two reviews providing a practical guide and fundamentals of cell migration: (1) How to select an optimal cell migration assay, (2) How to analyze cell migration data. We also added a perspective on AI methods of analysis. Coming out soon in Nature Methods.

More than 38 million Americans live with diabetes. At Johns Hopkins University, Joshua C. Doloff is developing biomaterials that could make Type 1 treatment safer and longer lasting. His lab’s NIH-funded work aims to improve lives and reduce complications. hub.jhu.edu/2025/03/18/nih… #FacultyFriday

📣Exciting announcement! hub.jhu.edu/2025/11/13/joh…

Register for the upcoming Advances in Immunoengineering Workshop starting on 1/5/26 which features speakers with topics on immune system fundamentals, engineering strategies to modulate the immune system, and clinical applications. Learn more here: inbt.jhu.edu/event/advances…

New online! Rethinking B cells in ulcerative colitis: a CAR T cell opportunity bit.ly/3LInn1C

As a deputy director at the Gates Foundation, #HopkinsBME alum Ari Moskowitz is leading a portfolio of investments and a team focused on medical devices and AI—tools that are transforming the way primary health care is delivered in underserved communities. bme.jhu.edu/news-events/ne…

Motivational video for #MigrationMovieMonday. A persistent 4T1 breast cancer cell squeezing itself through a tight constriction despite undergoing repetitive nuclear envelope rupture. Credit: Kristen Nedza Weill Institute for Cell & Molecular Biology Cornell University