🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

🔵📢Our study on adjuvant chemotherapy in biliary tract cancers has been published! I am very thankful to Angela Lamarca for her great mentoring and support along the way 🙏🏻 ✅5FU-based ChT: RFS and OS benefit in both short and long terms ❗️Benefit is apparent in short-term

Omitting bolus 5-FU in GI cancer chemo: a meta-analysis 🔬 pubmed.ncbi.nlm.nih.gov/40590359/ In 12,698 pts, skipping bolus 5-FU ➡️ ↓ grade 3–4 neutropenia (🧪 OR 0.46) & thrombocytopenia (🩸 OR 0.53) without compromising PFS or OS ✅ 💪Safer option, same efficacy.

Patterns in genomic mutations among patients with early-onset colorectal cancer: an international, multicohort, observational study - The Lancet Oncology thelancet.com/journals/lanon…

Anticipating this #GIonc study since #ESMO24 - LEANOX in Journal of Clinical Oncology #Lean body mass based #oxaliplatin dosing in stage III #crcsm ⬇️ #neurotox ⚡️🔥 and ⬆️ #QoL without ⬇️ #OS vs standard BSA-based dosing 💉 🔗: ascopubs.org/doi/10.1200/JC… OncoAlert🚨 ASCO PallOnc Community of Practice #OncoAlertAF

Important to note: "Compared with CROSS, perioperative chemotherapy with FLOT improved survival through better systemic tumor control with a reduction in distant tumor recurrences, while locoregional efficacy was similar."

I am riding 85 miles Pan-Mass Challenge to raise funds for Dana-Farber's Young-Onset Colorectal Cancer Center Please support if you can! profile.pmc.org/TJ0141?fbclid=…

The twin sins of institutional dysfunction Responsibility without authority Authority without responsibility

Jensen Huang: It's easier to fall in love with what you do than to find what you love “A lot of people say, ‘Find something you love.’ I don’t know about that. I guess I’ve fallen in love with many things that I do. I loved it when I was a dishwasher. I loved it when I was a

HIMALAYA is the 1st phase III trial to show 5-year OS in unresectable HCC! regular Durva/single Tremelimumab (Stride) 5-yr OS 19.6% vs 9.4% w/ Sorafenib ✅ Durable benefit ✅ No new late toxicities 🔹Benefit seen regardless of RECIST response #LiverCancer #HCC #Immunotherapy

His comments are truly insightful!

Tyler Miller, MD, PhD, pathologist and glioblastoma researcher at University Hospitals Seidman Cancer Center, recently published a key discovery that he and his team uncovered regarding myeloid cells. Remarkable research with real-world, clinical applications. uhhospitals.org/for-clinicians…

Imperative to think about the unique needs of these patients.

📺 In part 2 of a new interview, Sakti Chakrabarti, MD of University Hospitals highlights new data from the #BREAKWATER and CheckMate 8HW trials, showing significant survival improvements in high-risk metastatic #colorectalcancer populations: buff.ly/gtOw31T

Join me in Austin this September for a cutting-edge conference dedicated to discussing the latest advances in GI cancer research and care! Don’t miss this opportunity to stay at the forefront of GI oncology. Use my last name as a discount code for FREE registration:

"45-49 years: - CRC screening prevalence increased from 20.8% in to 33.7% in 2023 - colonoscopy prevalence increased from 19.5% in 2019 to 27.7% in 2023 - stool-based testing increased from 1.3% in 2019 to 7.1% in 2023" jamanetwork.com/journals/jama/…

Targeting the YAP-SDC1 axis overcomes resistance to KRASi in GI cancers by blocking SDC1-driven macropinocytosis and RTK activation, offering a promising strategy for KRASi resistance. Wantong Yao Haoqiang Ying Cell Reports Medicine #crcsm To the clinic! pubmed.ncbi.nlm.nih.gov/40713971/

What if it happens in 5-7 years! I will not be surprised.

Examining periop Checkpoint inhibitor benefit in gastro-esophageal cancer... sciencedirect.com/science/articl… Led by very talented Joseph J Zhao and Kennedy Ng. Raghav Sundar

Optimizing diet/exercise post treatment is becoming more and more important. Need to figure out models to operationalize this David Liska Smitha Krishnamurthi "being physically active & diet rich in vegetables fruits, whole grains after stage III colon cancer assoc w/ a longer survival"