PacBio vs Nanopore PacBio Oxford Nanopore - Final version - Acknowledgements to Karen Miga

* People ask LLMs to write code * LLMs recommend imports that don't actually exist * Attackers work out what these imports' names are, and create & upload them with malicious payloads * People using LLM-written code then auto-add malware themselves vulcan.io/blog/ai-halluc…

Pangene is a new tool for constructing a pangenome gene graph from multiple assemblies: github.com/lh3/pangene. You can explore the rich haplotypic diversity of human genes at pangene.liheng.org. Still WIP.

jstreeview is a HTML+JavaScript tree viewer/editor I initially developed for TreeFam in 2008. I now make it public with minor updates at github.com/lh3/jstreeview. Although 15 years old, jstreeview still has features rarely seen in other web-based or even desktop tree viewers.

I think we need to talk about how devastating this cancer microbiome refutation paper from Steven Salzberg 💙💛 and colleagues is. It really speaks to how devoid of critical thinking and intellectual depth our glam publishing ecosystem has become. 1/n biorxiv.org/content/10.110…

RNAseq counting tools are not perfect. I simulated 240 GTEx samples to test multiple tools. Below I show the difference between actual and estimated counts for each simulated sample. But, what is causing this? And will it affect differential expression? (1/7) #Bioinformatics

We are seeking an assistant/associate professor in bioinformatics/computational biology/AI in life sciences. ntu.wd3.myworkdayjobs.com/en-US/Careers/… The position comes with an attractive start-up fund, remuneration, and a very generous funding system. P.s. the place in the pic is <1 hour away.

Richard Durbin and I have been working on a review titled "Genome assembly in the telomere-to-telomere era". We have put the preprint at arxiv.org/abs/2308.07877. Let us know if you have comments or suggestions. We would really appreciate!

SAGB Agosto @labbces instagram.com/p/CwGSExGAVPy/… labbces.netlify.app/event/sagb-300…

Wondering how to best annotate #protein-coding genes in a genome? 🧬 Check out our new #structural annotation guide👉 erga-biodiversity.eu/structural-ann… Great work led by @ADennis1980 & the ERGA #Annotation Committee 🎉 Earth BioGenome Project 🌍 Biodiversity Genomics Europe (BGE)

from: nature.com/articles/s4159…

Thanks to @mariana_deniz and FocalPlane for the friendly interview and for allowing me to share my career path discovering the wonders of #evodevo. Special thanks to Luiza Saad, Denisse Galarza, and Juan Jimenez Merino for the #planarian, and #ascidian microscopic photos.

We’ve always wondered if there was something beyond CRISPR for genome editing. We now report that animals, plants, fungi and viruses have troves of programmable nucleases capable of efficient gene editing in human cells An update on our Fanzor work! science.org/doi/10.1126/sc… 1/7

GitHub re-founded on Copilot 🤯 Everyone will be able to write code. I'm certain. Todays upgrade to Copilot is a push in that direction

Early days of de novo genome assembly

K&R is, in fact, the only correct style for placing { and }.

If you think overpopulation is a problem, you may be wrong. Two centuries of rapid global population growth are coming to an end. World population growth is a first derivative, in math terms, and peaked in 1968, going down almost continually ever since UN projections show it

Verifying myself: I am diriano on Keybase.io. 1cK0C4kph4tq8Ijew50HxCjEkP0JofdbE25l / keybase.io/diriano/sigs/1…

It's the 6-week countdown to BGA24, and we currently sit at 30 unique sessions! You can join us at discord.gg/HBPytGx6sU to keep up to date with information and other attendees! Session list: thebgacademy.org/BGA24/BGA24 #BGA24 #Bioinformatics #Biodiversity #Genomics

So long San Diego! Here’s my opinionated meeting report from #PAG2025 | #PAG32. What else did I miss???