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Thank you to Wolfson Foundation for awarding Prof Oscar Marín and co-investigators at CDN | King's College £1.5 m to establish Brain Organoids Laboratory in the Centre for Human Brain Development. This funding equips our researchers with cutting-edge tools to investigate human brain development

Check out the The Leverhulme Trust feature on the exciting research by Laura Andreae and Karen Page, recipients of their Research Project Grant.🔬 Read more about their innovative work here: media.leverhulme.ac.uk/feature/andera…

Join us today at 1pm for our internal seminar series!

Dev Neuro Academy: Pathways to Discovery – a new short film by Asma Bashir – showcases the ethos, experiences, and impact of this flagship widening participation initiative at the Centre for Developmental Neurobiology. Watch here: youtu.be/FIt0n2eOFWk?si…

Only 1 week left to apply for a faculty position at the fantastic Wolfson SPaRC Are you doing phenomenal research into spinal cord & brain repair, chronic pain or sensory systems? Do you want to join a vibrant, collegiate Centre in the heart of London? If so, then please apply!

We are recruiting! We're looking for a dynamic, experienced Research Strategy Manager to join us. More details and application link: kcl.ac.uk/jobs/113925-re…

1/10 Our latest research, led by Martijn Selten, identifies a mechanism through which Parvalbumin (PV) interneurons regulate their activity in the #cortex. This is the story nature nature.com/articles/s4158… 🧵⬇︎ CDN | King's College CNDD| King's College Institute of Psychiatry, Psychology & Neuroscience European Research Council (ERC) Rosetrees Trust

2/10 The cortex contains two main classes of neurons: excitatory “go” pyramidal cells and inhibitory “no-go” #interneurons

3/10 Neuronal activity operates within a tightly controlled range for the optimal functioning of #brain circuits. When synaptic connectivity and network activity are modified, such as when we are learning, compensatory mechanisms are needed to maintain stability

4/10 Using experimental manipulations, we found that PV interneurons scale the inhibition they receive to maintain stability. When the activity of a PV interneuron increases, it “requests” more inhibitory inputs from other PV+ interneurons, effectively rebalancing its activity

5/10 How is this achieved? We found that PV interneurons induce the expression of two genes encoding multiple neuropeptides, Scg2 and Vgf, in response to increased activity

7/10 For PV interneurons, Vgf is the critical gene modulating the plasticity of inhibitory inputs received from other PV interneurons

9/10 In sum, our findings identify a previously unknown form of interneuron plasticity and strengthen the idea that neuropeptide signalling plays crucial roles in maintaining neural circuit stability. Funded by the magnificents European Research Council (ERC) and Rosetrees Trust

10/10 Here’s the paper nature if you want to dig in nature.com/articles/s4158… That’s it. Thanks for sharing! CDN | King's College CNDD| King's College Institute of Psychiatry, Psychology & Neuroscience European Research Council (ERC)

I am hiring!! Please share in your networks. Deadline to apply: 26th May 2025 kcl.ac.uk/jobs/114685-re…

New paper from Julie Jézéquel and the Beatriz Rico on role of cadherins in neuronal inhibition out now in Nature Communications! rdcu.be/el18f

We're #hiring for a new role as Senior EA to our wonderful Director and Managing Director! Deadline 23 June kcl.ac.uk/jobs/116505-se…

We're #hiring! Looking for an experienced and dynamic Research Strategy Manager... More details in link below Deadline 09 July kcl.ac.uk/jobs/118025-re…

Dr. Katie Long is leading vital research, funded by an MRF award, to learn how pregnant people feel about vaccines during pregnancy. We want your views! Take this short survey:: tinyurl.com/vaccines-in-pr… For more information on vaccines in pregnancy visit tommys.org/vaccinations-p…