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Following our field's inspiring history of building synthetic receptors, here we share our lab's first attempt at a post-transcriptional one. Based on ADAR-editing and compatible with various inputs/outputs.

very cool work from 2 of the coolest labs jared toettcher Daniel J. Cohen (CohenLab at Princeton). What is the deal with the flipped FGFR response?

Always thought open circulation = well mixed, which is apparently wrong. We def need more quantifications like this! Someone should do a whole body diffusion simulation and see how exactly the organs are communicating.

Magnetogenetics is coming!

Smart way of reverse translation!

Abstracts due *this Friday*!

Nature research paper: Endoplasmic reticulum–plasma membrane contact gradients direct cell migration go.nature.com/3RoZHzw

Cutiest mug with the cutiest protein on it! Thanks Will for leaving a lovely 3-year memory! Good luck with everything!

Wild that this idea is confirmed by experiments. Wondering how we survive with a generation time way longer than worms give the rapid evolution of pathogens: somatic dna diversification must have evolved before any animal can reach a certain life span? ncbi.nlm.nih.gov/pmc/articles/P…

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You’ve probably all seen the see-through mouse by now. Here’s a little more detail on how this optical trick works! Amazing work from HongLab in Science Magazine

Beautiful work tracking early stage symmetry breaking events with synthetic circuits! Congrats Harold, Jared and team!

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Excited to share our preprint describing hu.MAP3.0. Here we integrate >25k mass spectrometry experiments to place ~75% of human proteins into 15k protein complexes. biorxiv.org/content/10.110…

How we present the project is the opposite of how we actually do the project

Thrilled that our work on the functional effects of EML4-ALK assemblies in cancer cells is now published in Nature Communications. Herculean effort through 2.5+ years of peer review by David Gonzalez-Martinez and Lee Roth. nature.com/articles/s4146…

Researchers have voiced concerns after South Africa updated its health-research ethics guidelines to include a new section on heritable human genome editing go.nature.com/3OkqoDz

Science friends heading to the Other Place 🌌—let’s not lose each other in the void. Over the next few weeks, I'll try to put together some science "starter packs" of who to follow. Fill out this form to be included. bit.ly/sci-starterpack Share widely ❤️

Information makes life special, with which cells know how to handle materials and energy wisely, how to coordinate and form tissues, how to recognize danger and opportunities. cell.com/cell/fulltext/…

We had three compelling talks from Zikang (Dennis) Dennis Huang , Mariia and Jacopo Jacopo Pasqualini in the last session of YBM. See you all next month (7th July at 11am EDT)! Sign up here to stay updated: forms.gle/MF2Q2jpeeqxyZJ…