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Animal Stem cells probably appeared 700-800 million years ago. We found that two key molecules that make our stem cells the way they are even older than that as they even existed before the evolution of animals. 1/n

Very cool and relevant work and another example of the modular evolution of transcriptional networks at the onset of animals. Here, Sox and POU are shown to be present in choanoflagellates, filastereans and, potentially, corallochytreans. So, yes, the unicellular ancestor

"The study implies that key genes involved in stem cell formation might have originated far earlier than the stem cells themselves, perhaps helping pave the way for the multicellular life we see today." nature.com/articles/s4146…

Happy to see our work on Sox/POU origins covered in detail at the The Washington Post by Kasha Patel. Thanks to BEAP Lab (Biology & Ecology of Abundant Protists) and Sandie Degnan for their contributions: washingtonpost.com/climate-enviro…

Before there were animals, there were transcription factors! Researchers in Drs. Alex de Mendoza's (Alex de Mendoza) and Ralf Jauch's (Ralf Jauch) teams showed that Sox and POU factors predate animal stem cells. 📑 Nature Communications: go.nature.com/49dsMFx 🎙️: bit.ly/4g70Sxm

Breaking paradigms: Finding 6mA DNA methylation in eukaryotes Francisco Falcon Francisco Falcon highlights research from Alex de Mendoza and team on 6mA in eukaryotes. #preprint #preLights 👀⤵️ prelights.biologists.com/highlights/ade…

Thrilled and honoured to be selected as an EMBO Installation Grant fellow! 🎉

🚀 We’ve just kicked off our DNA Methylation course! 🎉 StartiStartedng strong with two brilliant lectures by Alex de Mendoza and Dr Hollie Marshall , setting the stage for an exciting hands-on session with James Ord . 🔬🧬

I am thrilled to announce that I’ve been awarded the Marie Skłodowska-Curie Fellowship! I will join Alex de Mendoza group at Queen Mary University of London 🇬🇧 to investigate the evolution of small RNAs in the context of endogenous giant virus, using unicellular eukaryotes as main models #SMALLGIANT #MSCA

We're excited to announce the official QMUL Centre for Epigenetics Launch Conference 2025! 🎉 To find out more and book your free ticket, please follow the link below: eventbrite.co.uk/e/qmul-centre-… Queen Mary University of London Barts Charity Blizard Institute @qmulepigenetics

🚀 What a great week! 🧬 Huge thanks to Dr Hollie Marshall James Ord and Alex de Mendoza for delivering an amazing course on DNA Methylation in Ecology & Evolution! 🙌 Shout-out to our attendees whose engagement and curiosity made every session both enriching and enjoyable! 💡✨

🚨Registration for the UK #EvoDevo meeting is open! Join us on July 11th Queen Mary University of London to enjoy an exciting day of talks, posters, friends, and superb science! -Registration: shorturl.at/9cQGL -More info: londonevodevo.ac.uk Supported by Azenta Life Sciences Novogene Europe